Results 21 to 30 of about 44,900 (251)
Extracellular traps and the role in thrombosis
Frontiers in Cardiovascular Medicine, 2022 Thrombotic complications pose serious health risks worldwide. A significant change in our understanding of the pathophysiology of thrombosis has occurred since the discovery of extracellular traps (ETs) and their prothrombotic properties. As a result of immune cells decondensing chromatin into extracellular fibers, ETs promote thrombus formation by ...
Tonglei Han +6 more
openaire +3 more sources
Neutrophil Extracellular Traps [PDF]
, 2013 Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state. The role of NETs in cancer biology and tumor progression may prove much more than
Viviana Marin-Esteban +2 more
+6 more sources
Surgery Open Science, 2020 Background: Colorectal cancer is the third most common cancer worldwide. Almost half of those that have a potentially curative resection go on to develop metastatic disease.
Georgia M. Carroll, BMed, PGDip +7 more
doaj +1 more source
Frontiers in Microbiology, 2021 Eosinophils are granulocytes classically involved in allergic diseases and in the host immune responses to helminths, fungi, bacteria and viruses.
Marina Valente Barroso +9 more
doaj +1 more source
Candida Extracellular Nucleotide Metabolism Promotes Neutrophils Extracellular Traps Escape
Frontiers in Cellular and Infection Microbiology, 2021 Host innate immunity is fundamental to the resistance against Candida albicans and Candida glabrata infection, two of the most important agents contributing to human fungal infections.
Mariana Afonso +10 more
doaj +1 more source
Neutrophil Extracellular Traps in Host Defense [PDF]
Cold Spring Harbor Perspectives in Biology, 2019 Neutrophils are produced in the bone marrow and then patrol blood vessels from which they can be rapidly recruited to a site of infection. Neutrophils bind, engulf, and efficiently kill invading microbes via a suite of defense mechanisms. Diverse extracellular and intracellular microbes induce neutrophils to extrude neutrophil extracellular traps (NETs)
Sabrina Sofia Burgener, Kate Schroder
openaire +5 more sources
Frontiers in Immunology, 2021 BackgroundExtracellular traps (ETs) and tumor-infiltrating immune cells can contribute to disease progression. The clinical significance of tumor-infiltrating neutrophils and macrophages and related extracellular traps in pancreatic neuroendocrine tumors
Shuai-Shuai Xu +63 more
doaj +1 more source
Multiple Origins of Extracellular DNA Traps
Frontiers in Immunology, 2021 Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms present in protozoa, plants, and animals. In this review, we compare their similarities in species of different taxa, and put forward the hypothesis that ETs have ...
Edgar Ramos-Martínez +9 more
doaj +1 more source
Neutrophil and Eosinophil DNA Extracellular Trap Formation: Lessons From Pathogenic Fungi
Frontiers in Microbiology, 2021 Fungal infections represent a worldwide health problem. Fungal pathogens are responsible for a variety of conditions, including superficial diseases, allergic pathologies and potentially lethal invasive infections.
Juliana da Costa Silva +5 more
doaj +1 more source
Neutrophil Extracellular Traps in Skin Diseases
Biomedicines, 2021 Neutrophils are the primary innate immune cells, and serve as sentinels for invading pathogens. To this end, neutrophils exert their effector functions via phagocytosis, degranulation, reactive oxygen species generation, and neutrophil extracellular trap
Youichi Ogawa +4 more
doaj +1 more source