Results 191 to 200 of about 1,588,316 (303)

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

A method for isolating small extracellular vesicles from parenchymal tissues

Extracellular Vesicle
Extracellular vesicles (EV) are released by almost all cells into the extracellular space, where they navigate through the interstitium or transfer bioactive molecules into neighboring cells, thereby regulating tissue homeostasis.
Yanan Sun, Junqing An, Jie Yuan, Chaoshan Han, Gangjian Qin   +4 more
doaj   +1 more source

A Noninvasive Approach to Study Localized Forces in 3D Epithelia

Advanced Materials, EarlyView.
Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand, Muhamet Ibrahimi, Claire Valotteau, Brice Lecouffe, André Le Bivic, Dominique Massey‐Harroche, Felix Rico, Matthias Merkel, Delphine Delacour, Elsa Bazellières   +9 more
wiley   +1 more source

Therapeutic potential of extracellular vesicles in inflammatory diseases

Extracellular Vesicle
Extracellular vesicles are spherical lipid bilayer vesicles composed of lipids, proteins and nucleic acids that could deliver signaling molecules into target cells to regulate their function and biological processes.
Xiaojian Huang, Shen Zhang, Zhenzhen Wang   +2 more
doaj   +1 more source

Life‐Like Ferrous Oxide Microspheres from Kombucha

Advanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis, Anna Nikolaidou, Andrew Adamatzky   +2 more
wiley   +1 more source

Composition of Pb3 and Pb18 extracellular vesicle and whole yeast cell total sterols identified by GC-MS. TR, trace amounts.

, 2012
Composition of Pb3 and Pb18 extracellular vesicle and whole yeast cell total sterols identified by GC-MS. TR, trace amounts.
Larissa V. G. Longo (156380), Alisson L. Matsuo (156387), Felipe G. Lopes (156385), Milene C. Vallejo (156375), Igor C. Almeida (156388), Ernesto S. Nakayasu (156378), Rosana Puccia (156390), Luciane Ganiko (156382)   +7 more
core   +1 more source

Mapping growth and trajectory in the field of extracellular vesicles: A scientometric analysis

Extracellular Vesicle
Extracellular vesicles (EVs) are a diverse population of membrane bound particles released by cells. They play roles in a variety of diseases and biological functions, piquing the interest of researchers and industry alike.
Liam Hourigan, William Phillips, Amirmohammad Nasiri Kenari, Krishna Chaitanya Pavani, Chaomei Chen, An Hendrix, Lesley Cheng, Andrew F. Hill   +7 more
doaj   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges

Advanced Robotics Research, EarlyView.
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source