Results 181 to 190 of about 1,588,316 (303)

Extracellular vesicles for breast cancer diagnosis and therapy

Extracellular Vesicle
Breast cancer is still suffering from its poor diagnosis and the lack of effective treatment. Despite of recent development of some novel chemicals, which are found to have inspiring therapeutic effects in vitro, their outcomes in clinic trails are ...
Jianan Shi, Huan Zhang, Yaxin Cui, Jianming Xing, Wei Wang, Jiayi Chen, Simiao Wang, Zhaogang Yang   +7 more
doaj   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

Proceedings of the National Academy of Sciences of the United States of America, 2016
J. Kowal, Guillaume Arras, Marina Colombo, M. Jouve, Jakob Paul Morath, Bjarke Primdal-Bengtson, F. Dingli, D. Loew, M. Tkach, C. Théry   +9 more
semanticscholar   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Biocompatible Conjugated Electrospinning Nanofibrous Membrane With Self‐Powered Piezoelectric Capacity for Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
A self‐powered PCL/gelatin‐PVDF‐TrFE/MXene conjugated electrospun membrane integrates biocompatibility with enhanced piezoelectric responsiveness. Mechanical deformation is converted into localized electrical signals that stimulate wound‐repair cells proliferation and migration, promote angiogenesis and tissue remodeling, and accelerate full‐thickness ...
Diandian Li, Ke Wu, Yangyang Lu, Qinglan Xia, Jialong Chen, Yifan Zhang, Zhaoyu Chen, Zhiyuan She, Junjin Jie, Juzi Xia, Muran Zhou, Aimei Zhong   +11 more
wiley   +1 more source

From hope to healing: Exploring the therapeutic potential of exosomes in spinal cord injury

Extracellular Vesicle
Spinal cord injury (SCI) is the damage to the spinal cord causing paralysis below the injury site causing compromised patient life quality. Exosomes are nanosized vesicles released during physiological or pathological processes.
Nidhi Singh, Lahanya Guha, Hemant Kumar
doaj   +1 more source

A 3D‐Printed Model of Human Lactation

Advanced Healthcare Materials, EarlyView.
Breastfeeding supports infant and maternal health, yet in vitro models that mimic human lactation remain scarce. Here, light‐based 3D printing creates high‐resolution, alveoli‐inspired microwells that guide breast cells into polarized microtissues. The printed scaffolds embed slow‐release prolactin microcrystals to deliver hormonal cues, enabling human
Amelia Hasenauer, Marcy Zenobi‐Wong
wiley   +1 more source

Packaging of humanized anti-HER2 monoclonal antibody into small extracellular vesicles

Extracellular Vesicle
Small extracellular vesicles (sEVs), including exosomes and microvesicles (MVs), are nano-sized membranous particles shed by almost all cell types. Both play significant roles in cellular communication by transferring proteins, nucleic acids, lipids, and
Junxin Mai, Yuanmei Zhang, Zhixuan Liang, Wei Xu, Qian Shao, Jingwen Peng, Jing Chen, Yuting Shentu, Zixin Chen, Juling Ji, Yuhua Ji, Qiuling Xie   +11 more
doaj   +1 more source

Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health

Advanced Materials, EarlyView.
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim, Seungwon Yoo, Tae Woog Kang, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source

Extracellular vesicle NTA counts.

, 2017
Population size distributions of extracellular vesicles in rat plasma. A. Fluorescence histograms of di-8 intensity (proportional to vesicle surface area) of EVs in rat plasma 1 hour and 24 hours after treatment with vehicle or LPS.
Jennifer B. Pierson (3636556), Padma K. Narayanan (3636559), Elizabeth G. Besteman (3636538), Karol L. Thompson (13311), James R. Turk (3636535), Alan Y. Chiang (3636544), John P. Nolan (1326981), Cindy E. Fishman (3636547), Abraham Guerrero (689135), April Paulman (3636562), Dennis W. Wilson (841686), Marjory B. Brooks (3636553), Heidrun Ellinger-Ziegelbauer (564123), Albert E. Schultze (3636550), Roberta A. Thomas (3636541)   +14 more
core   +1 more source