Results 161 to 170 of about 1,588,316 (303)
Extracellular VesicleThe bone marrow (BM) microenvironment relies on extracellular vesicle (EV)-mediated communication to maintain hematopoietic homeostasis and contribute to cellular responses in malignant transformation.
Federica Zanotti +6 more
doaj +1 more source
Journal of Extracellular Vesicles, 2019 The expanding field of extracellular vesicle (EV) research needs reproducible and accurate methods to characterize single EVs. Nanoparticle Tracking Analysis (NTA) is commonly used to determine EV concentration and diameter.
Daniel Bachurski +10 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.To mimic the LH action in the ovary, granulosa‐cell and mouse models were stimulated by hCG, which changed RNA profiles within extracellular vesicles (EVs), and potentially hCG‐responsive EV RNAs increased the number of recipient ovarian cells. EV‐associated RNAs are potential intermediaries of hCG signaling.
Natchanok Puangjit +6 more
wiley +1 more source
Novel administration strategies for tissue-specific delivery of extracellular vesicles
Extracellular VesicleExtracellular vesicles (EVs) are nanoparticles released by cells with bilayer lipid membranes that have been demonstrated to regulate biological activities. The potential of EVs as a novel therapeutic or drug delivery platform has already been identified
Junyao Deng, Qishan Li, Fei Wang
doaj +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
, 2013 Secretion of extracellular vesicles is a general cellular activity that spans the range from simple unicellular organisms (e.g. archaea; Gram-positive and Gram-negative bacteria) to complex multicellular ones, suggesting that this extracellular vesicle ...
Go, Gyeongyun +42 more
core +1 more source
Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking
Experimental and Molecular Medicine, 2019 Extracellular vesicles (EVs) are increasingly being recognized as mediators of intercellular signaling via the delivery of effector molecules. Interestingly, certain types of EVs are also capable of inducing therapeutic responses.
Daniel E. Murphy +6 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Characterization of a Cell-Culturing System for the Study of Contact-Independent Extracellular Vesicle Communication [PDF]
, 2016 Appropriate and well-documented in vitro cell-culturing systems are necessary to study the activity and biological function of extracellular vesicles (EVs).
Rikke Bæk +14 more
core +1 more source