Results 141 to 150 of about 1,588,316 (303)
Exosome as drug delivery system: Current advancements
Extracellular VesicleExosomes are nanovesicles released from cells due to pathophysiological events. These nanoparticles are resistant to metabolic destruction and can transcend the blood-brain barrier. Exosome therapy could be employed as precision medicine by targeting the
Vriti Sharma +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
, 2019 Extracellular vesicle preparation western blot profiles of somatic (10 μg protein), excretory-secretory protein (10 μg protein), soluble extracellular vesicle protein (20 μg protein) and insoluble extracellular vesicle protein (20 μg protein). Biological
Peter M. Brophy (162777) +6 more
core +1 more source
, 2022 Supplementary Data from Extracellular Vesicle–Packaged CDH11 and ITGA5 Induce the Premetastatic Niche for Bone Colonization of Breast Cancer ...
Xiao-Qing Li (14956098) +4 more
core +1 more source
Extracellular vesicle lyophilization for enhanced distribution to the point of care
Extracellular VesicleTherapeutic extracellular vesicles (EVs) are in clinical trials and if successful, EVs wider use will be largely affected by costs to patients/insurers and accessibility.
Morgane E. Golan, Steven L. Stice
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Extracellular vesicle-derived small RNA in acute kidney injury progression.
Extracellular vesicle-derived small RNA profiling in acute kidney injury ...
Kassianos, Andrew
core +1 more source
Systematic characterization of mammalian extracellular vesicles using nano-flow cytometry
Extracellular VesicleExtracellular vesicles (EVs) are nanoscale, membrane-enclosed particles that transport bioactive cargo between cells and are increasingly studied for their potential in diagnostic and therapeutic applications.
Benjamin T. Vyzourek +8 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Extracellular vesicle-based targeted RNA therapies against cancer
Extracellular VesicleExtracellular vesicles (EVs) are nanoscale vesicles released by cells and serve as natural carriers for RNAs, DNAs, proteins, and lipids that mediate intercellular communication.
Ziqi Wang +3 more
doaj +1 more source