Results 121 to 130 of about 1,588,316 (303)

Differential small extracellular vesicle (sEV) small non-coding RNA (ncRNA) cargo across study subjects and biofluids.

, 2020
Differential small extracellular vesicle (sEV) small non-coding RNA (ncRNA) cargo across study subjects and biofluids.
Xiang Zhang (19800), Mario Medvedovic (1779), Damaris Kuhnell (6171257), Katherine A. Burns (8697645), Glenn G. Talaska (8697642), Scott M. Langevin (6171254), Jacek Biesiada (438811), Susan Kasper (824702)   +7 more
core   +1 more source

Sensory cilia act as a specialized venue for regulated extracellular vesicle biogenesis and signaling.

, 2021
Ciliary extracellular vesicle (EV) shedding is evolutionarily conserved. In Chlamydomonas and C.
Akella, Jyothi S, Nikonorova, Inna A, Barr, Maureen M, Walsh, Jonathon D, Silva, Malan, Gu, Amanda, DMD, Tilton, Peter E, Wang, Juan   +7 more
core   +1 more source

Ultrasonication outperforms electroporation for extracellular vesicle cargo depletion

Extracellular Vesicle
Extracellular vesicles (EVs), submicron-sized membranous structures released by cells, serve as vehicles of tissue-specific proteins and nucleic acids, facilitating intercellular communication and playing roles in pathophysiological processes. Leveraging
Yundi Chen, Le Wang, Xu Yu, Wenjun Mao, Yuan Wan   +4 more
doaj   +1 more source

Extracellular vesicles and aging [PDF]

Stem Cell Investigation, 2017
Aging and the chronic diseases associated with aging place a tremendous burden on our healthcare system. As our world population ages dramatically over the next decades, this will only increase. Hence, there is a great need to discover fundamental mechanisms of aging to enable development of strategies for minimizing the impact of aging on our health ...
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Accelerating extracellular vesicle research and biotechnological applications using synthetic biology approaches

Can a combination of the extracellular vesicle (EV) research community’s latest consensus guidance (MISEV2023) along with synthetic biology’s engineering approaches and responsible innovation framework help to accelerate future EV-based industrial and ...
Freemont, Paul, Alexander J. Webb, Richard J.R. Kelwick, Webb, Alexander, Kelwick, Richard, Paul S. Freemont   +5 more
core   +1 more source

An extracellular vesicle delivery platform based on the PTTG1IP protein

Extracellular Vesicle
Extracellular vesicles (EVs) are promising therapeutic delivery vehicles, although their potential is limited by a lack of efficient engineering strategies to enhance loading and functional cargo delivery.
Carla Martin Perez, Xiuming Liang, Dhanu Gupta, Emily R. Haughton, Mariana Conceição, Imre Mäger, Samir EL Andaloussi, Matthew J.A. Wood, Thomas C. Roberts   +8 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Emerging technologies for profiling extracellular vesicle heterogeneity

, 2020
Approaches, challenges and promising opportunities towards decoding the complexity of extracellular vesicle heterogeneity are discussed.
G Lin (7939241), D Jin (13449051), Wei Duan (13099662), Y Zhu (6338063), G Huang (7750961)   +4 more
core  

P2X7 Receptor and Extracellular Vesicle Release

, 2023
Extensive evidence indicates that the activation of the P2X7 receptor (P2X7R), an ATP-gated ion channel highly expressed in immune and brain cells, is strictly associated with the release of extracellular vesicles.
Martina Gabrielli, Claudia Verderio, Maria Teresa Golia, Golia, Maria Teresa, Verderio, Claudia, Gabrielli, Martina   +5 more
core   +1 more source