Results 101 to 110 of about 215,428 (267)

From hope to healing: Exploring the therapeutic potential of exosomes in spinal cord injury

Extracellular Vesicle
Spinal cord injury (SCI) is the damage to the spinal cord causing paralysis below the injury site causing compromised patient life quality. Exosomes are nanosized vesicles released during physiological or pathological processes.
Nidhi Singh, Lahanya Guha, Hemant Kumar
doaj   +1 more source

Vascularization of Human iPSC‐Derived Kidney Organoids Using Perfusion Culture, Pre‐Vascularized Collagen Scaffolds, and Decellularized Extracellular Matrix

Advanced Healthcare Materials, EarlyView.
An integrated perfusion‐based culture platform combining pre‐vascularized collagen scaffolds, stromal vascular fraction cells, and kidney decellularized extracellular matrix promotes vascularization of human iPSC‐derived kidney organoids. The platform provides evidence of interactions between vascular networks and glomerular‐like structures and enables
Helen Kearney, Andrea Mazzoleni, Ivan Martin, Lorenzo Moroni, Manuele Giuseppe Muraro, Carlos Mota   +5 more
wiley   +1 more source

Packaging of humanized anti-HER2 monoclonal antibody into small extracellular vesicles

Extracellular Vesicle
Small extracellular vesicles (sEVs), including exosomes and microvesicles (MVs), are nano-sized membranous particles shed by almost all cell types. Both play significant roles in cellular communication by transferring proteins, nucleic acids, lipids, and
Junxin Mai, Yuanmei Zhang, Zhixuan Liang, Wei Xu, Qian Shao, Jingwen Peng, Jing Chen, Yuting Shentu, Zixin Chen, Juling Ji, Yuhua Ji, Qiuling Xie   +11 more
doaj   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

A method for isolating small extracellular vesicles from parenchymal tissues

Extracellular Vesicle
Extracellular vesicles (EV) are released by almost all cells into the extracellular space, where they navigate through the interstitium or transfer bioactive molecules into neighboring cells, thereby regulating tissue homeostasis.
Yanan Sun, Junqing An, Jie Yuan, Chaoshan Han, Gangjian Qin   +4 more
doaj   +1 more source

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, EarlyView.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source

Therapeutic potential of extracellular vesicles in inflammatory diseases

Extracellular Vesicle
Extracellular vesicles are spherical lipid bilayer vesicles composed of lipids, proteins and nucleic acids that could deliver signaling molecules into target cells to regulate their function and biological processes.
Xiaojian Huang, Shen Zhang, Zhenzhen Wang   +2 more
doaj   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

Advanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase, Varsha C. Pujari, Akash V. Fulari, Sunil M. Patange, Sean Li, Danyang Wang, Sagar E. Shirsath   +6 more
wiley   +1 more source

Mapping growth and trajectory in the field of extracellular vesicles: A scientometric analysis

Extracellular Vesicle
Extracellular vesicles (EVs) are a diverse population of membrane bound particles released by cells. They play roles in a variety of diseases and biological functions, piquing the interest of researchers and industry alike.
Liam Hourigan, William Phillips, Amirmohammad Nasiri Kenari, Krishna Chaitanya Pavani, Chaomei Chen, An Hendrix, Lesley Cheng, Andrew F. Hill   +7 more
doaj   +1 more source