Results 211 to 220 of about 236,767 (310)

Single-molecule localization microscopy imaging of extracellular vesicle DNA in recipient cells. [PDF]

J Transl Med
Zhu X, Chetty VK, Ghanam J, Hila A, Yang Q, Strickfaden H, Bonn M, Cremer C, Hoyer PF, Liu X, Thakur BK.   +10 more
europepmc   +1 more source

Extracellular Vesicle Secretion Dynamics and lipid composition in human multipotent adipose-derived stem cells from Lean and Obese donors

MENNENS, Lisa, Verbunt, Jari, Jocken, Johan, HOSSEINKHANI, Baharak, Blaak, Ellen, VERBOVEN, Kenneth   +5 more
openalex   +1 more source

Quality and efficiency assessment of five extracellular vesicle isolation methods using the resistive pulse sensing strategy

Min Yang, Jia Guo, Le Fang, Ze Chen, Ying Liu, Zepeng Sun, X.F. Pang, Yinghua Peng   +7 more
openalex   +2 more sources

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Clinical Implications of Plasma-Derived Extracellular Vesicles in Myeloproliferative Neoplasms: Unveiling Inflammatory Potential and Biomarkers for Cancer Treatment [PDF]

Ghazal Narimanfar, Dorian Forte, Roberto Maria Pellegrino, Francesca Perut, Filippo Maltoni, Martina Barone, Alessia Brancolini, Filippo Branzanti, Vincenzo Pucci, Elisabetta Lugli, Alessia Tieghi, Carla Emiliani, Johannes Grillari, Pier Luigi Zinzani, Francesca Palandri, Lucia Catani   +15 more
openalex   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Plasma-Derived Extracellular Vesicle Proteomics. [PDF]

J Proteome Res
Tan Y, Kao WC, Boppart M, Sweedler JV.
europepmc   +1 more source

Bafilomycin A1 Potentially Enhances Mesenchymal Stem Cell-derived Extracellular Vesicle Production in iPSC-MSC Cultures [PDF]

Yuping Xiao, Weiyi Yuan, Shihong Chen, Gensheng Zhang, Qing‐Ling Fu, Zhijian Cai, Xinliang Lu   +6 more
openalex   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source