Results 241 to 250 of about 236,767 (310)

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Therapeutic extracellular vesicle preparation <i>via</i> sequential electrophoretic enrichment and counterflow microdialysis.

Lab Chip
Mehraji S, Pirolli NH, Nowak R, Jay SM, DeVoe DL.   +4 more
europepmc   +1 more source

Orthogonal Investigation at Single-Particle and Ensemble Levels Uncovers Lipoprotein-Extracellular Vesicle Binding. [PDF]

Anal Chem
Musicò A, Frigerio R, Normak K, Scolari S, Gori A, Arosio P, Radeghieri A, Paolini L, Romano M, Llarena I, Moya SE, Zendrini A, Bergese P.   +12 more
europepmc   +1 more source

Physical and functional characterisation of apoptotic cell- derived extracellular vesicles [PDF]

, 2014
Lois Hawkins, Khaled Alghareeb, Vinod Nadella, Parbata Chauhan, Charlotte E. Bland, Andrew Devitt   +5 more
openalex  

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Advanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng, Metoboroghene Mowoe, Wenqing Hou, Daniel W. Hagey, Koshi Imami, Samir EL Andaloussi   +5 more
wiley   +1 more source

Erratum to “MicroRNAs won the Nobel Prize. Now, can extracellular vesicles help them become drugs?” [Extracell Vesicle 5 (2025) 100080]

Extracellular Vesicle
Vanessa YiRan Li, Nicole Rosas, Sharon Fleischer, Gordana Vunjak-Novakovic, Ke Cheng   +4 more
doaj   +1 more source

Role of small extracellular-vesicle microRNA-302f in endometriosis-associated ovarian cancer. [PDF]

Discov Oncol
Tsai CC, Hsu CY, Lin HY, Suen JL, Ou YC, Tsai EM.   +5 more
europepmc   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Extracellular Vesicle-Based Therapeutic Cargo Delivery for Cancer Therapy. [PDF]

Int J Nanomedicine
Huang Z, Cheng J, Deng Z, Liu C, Huang T, Lin W.   +5 more
europepmc   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source