Results 241 to 250 of about 319,764 (352)

TurboID-Mediated Profiling of Glioblastoma-Derived Extracellular Vesicle Cargo Proteins. [PDF]

J Extracell Vesicles
Russo MN, Norton ES, Ulloa-Navas MJ, Zarco N, Wang W, Lam TT, Quiñones-Hinojosa A, Belzil VV, Guerrero-Cázares H.   +8 more
europepmc   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

MITF regulates autophagy and extracellular vesicle cargo in gastrointestinal stromal tumors. [PDF]

Mol Biomed
Proaño-Pérez E, Serrano-Candelas E, Guerrero M, Gómez-Peregrina D, Llorens C, Soriano B, Gámez-Valero A, Herrero-Lorenzo M, Martí E, Serrano C, Martin M.   +10 more
europepmc   +1 more source

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source

Extracellular vesicle-derived miR21 of non-tumoral origin as early diagnostic marker of glioma. [PDF]

J Neuroinflammation
De Luca M, Rinaldi A, Ioni A, Oudin A, Scafidi A, Poli A, Vilardo L, Golebiewska A, D'Agnano I, Michelucci A, Limatola C, Catalano M.   +11 more
europepmc   +1 more source

Clathrin couture: Fashioning distinctive membrane coats at the cell surface [PDF]

, 2009
B. M Collins, B. T Kelly, C Raiborg, C. J Merrifield, D Leonard, D Loerke, D. A Sanan, D. K Cureton, E Boucrot, E. M Schmid, F. Z Idrissi, I Gaidarov, J Barroso-Gonzalez, J Heuser, J Heuser, J Rosenbluth, J. Z Rappoport, J. Z Rappoport, K Miller, K. D Bellve, L Hinrichsen, Linton M. Traub, M Ehrlich, M Kaksonen, M Lakadamyali, M. A Puthenveedu, M. C Saleh, N Abe, P Maupin, P Varnai, P. A Keyel, P. A Keyel, R Zoncu, S Mayor, S Saffarian, S. J Mundell, T Akisaka, T Ben-Kasus, T Kirchhausen, T. A Gottlieb, T. F Roth, X Wu   +41 more
core   +4 more sources

Biosensing of red blood cell-derived extracellular vesicles with the advanced bright-field light optical polarization microscopy [PDF]

, 2017
Alexander Е. Berezin, Richard E Mokhnach, Harry A Byalik   +2 more
openalex   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

The role of natural compounds in modulation of small extracellular vesicle biogenesis and lipid metabolism in cancer. [PDF]

Front Mol Biosci
Lim GY, Santhakumar L, Mielczarek-Puta M, Skrzycki M.   +3 more
europepmc   +1 more source

Granulocyte-derived extracellular vesicles activate monocytes and are associated with mortality in intensive care unit patients [PDF]

, 2018
Adelman, Avril, et al,, Schechtman, Kenneth B, Spinella, Philip C   +3 more
core   +1 more source