Results 21 to 30 of about 206,828 (334)

Machine Intelligence-Driven Classification of Cancer Patients-Derived Extracellular Vesicles using Fluorescence Correlation Spectroscopy: Results from a Pilot Study [PDF]

Neural Computing and Applications (2023), 2022
Patient-derived extracellular vesicles (EVs) that contains a complex biological cargo is a valuable source of liquid biopsy diagnostics to aid in early detection, cancer screening, and precision nanotherapeutics. In this study, we predicted that coupling cancer patient blood-derived EVs to time-resolved spectroscopy and artificial intelligence (AI ...
arxiv   +1 more source

Towards rapid extracellular vesicles colorimetric detection using optofluidics-enhanced color-changing optical metasurface [PDF]

, 2023
Efficient transportation and delivery of analytes to the surface of optical sensors are crucial for overcoming limitations in diffusion-limited transport and analyte sensing. In this study, we propose a novel approach that combines metasurface optics with optofluidics-enabled active transport of extracellular vesicles (EVs).
arxiv   +1 more source

Is your article EV-TRACKed? [PDF]

, 2017
The EV-TRACK knowledgebase is developed to cope with the need for transparency and rigour to increase reproducibility and facilitate standardization of extracellular vesicle (EV) research.
Jan Van Deun, An Hendrix, null null
core   +1 more source

Quality of approximating a mass-emitting object by a point source in a diffusion model [PDF]

, 2023
For the sake of computational efficiency and for theoretical purposes, in mathematical modelling, the Dirac Delta distributions are often utilized as a replacement for cells or vesicles, since the size of cells or vesicles is much smaller than the size of the surrounding tissues.
arxiv   +1 more source

AOC; Assembling Overlapping Communities [PDF]

Quantitative Science Studies (2022), 2022
Through discovery of meso-scale structures, community detection methods contribute to the understanding of complex networks. Many community finding methods, however, rely on disjoint clustering techniques, in which node membership is restricted to one community or cluster.
arxiv   +1 more source

Scalable trapping of single nanosized extracellular vesicles using plasmonics [PDF]

, 2023
Heterogeneous nanoscale particles released by cells known as extracellular vesicles (EVs) are actively investigated for early disease detection1, monitoring2, and advanced therapeutics3. Due to their extremely small size, the stable trapping of nano-sized EVs using diffraction-limited optical tweezers4 has been met with challenges.
arxiv   +1 more source

Ambient but not local lactate underlies neuronal tolerance to prolonged glucose deprivation [PDF]

, 2018
Neurons require a nearly constant supply of ATP. Glucose is the predominant source of brain ATP, but the direct effects of prolonged glucose deprivation on neuronal viability and function remain unclear.
Mennerick, Steven, Shu, Hong-Jin, Sobieski, Courtney, Warikoo, Natasha   +3 more
core   +2 more sources

Plasmonic dielectric antennas for hybrid optical nanotweezing and optothermoelectric manipulation of single nanosized extracellular vesicles [PDF]

arXiv, 2023
We present an experimental demonstration of near-field optical trapping and dynamic manipulation of a single extracellular vesicle using a plasmonic dielectric nanoantenna that supports an optical anapole state. The optical anapole is a non-radiating optical state generated by the destructive interference between electric and toroidal dipoles in the ...
arxiv  

Determining the neurotransmitter concentration profile at active synapses [PDF]

, 2009
Establishing the temporal and concentration profiles of neurotransmitters during synaptic release is an essential step towards understanding the basic properties of inter-neuronal communication in the central nervous system.
A Barberis, A Scimemi, A Tao, A Triller, AE Spruce, AG Ogston, AI Gulyas, AM Aravanis, Annalisa Scimemi, AV Hill, B Barbour, B Ceccarelli, B Granseth, B Katz, C Auger, C Nicholson, C Nicholson, C Nicholson, C Racca, D Colquhoun, D Colquhoun, D Sulzer, DA Rusakov, DE Bergles, DM Kullmann, DR Copenhagen, E Betzig, E Neher, E Sykova, EL Botvinick, EN Pothos, EP Huang, F Asztely, F Pouille, G Brasnjo, G Liu, G Szapiro, G Tong, GH Acheson, GH Patterson, H Korn, H Korn, H Shroff, HC Hartzell, IM Raman, J Balaji, J Castillo Del, J Hrabe, J Matthews-Bellinger, J Szabadics, JC Eccles, JC Eccles, JC Eccles, JD Clements, JE Heuser, JH Singer, JI Wadiche, JI Wadiche, JJ Celentano, JM Bekkers, JM Christie, JM Fernandez, JR Stiles, JS Diamond, JS Diamond, JS Diamond, JW Mozrzymas, JW Mozrzymas, K Belaya, K Krnjevic, K Luby-Phelps, K Zheng, KA Foster, KE Sorra, KL Magleby, KM Franks, KP Lehre, L He, L Tao, LG Longsworth, LM Levy, LM Wahl, LP Savtchenko, LS Overstreet, M Beato, M Beato, M Beato, MA Medina, Marco Beato, MI Banks, MJ Higley, MV Jones, MY Min, N Arnth-Jensen, N Harata, N Riveros, NC Harata, O Prange, P Fatt, P Fatt, P Legendre, PJ Kruk, PM Burger, Q Zhang, Q Zhang, R Ando, R Conti, R Renden, R Ventura, RG Thorne, RH Chow, RM Wightman, RW Daniels, RY Tsien, S Habuchi, S Hrabetova, S Manley, S Namiki, S Okumoto, S Takamori, SA Hires, SJ Pitt, SP Gandhi, SW Kuffler, SY Breusegem, T Lu, T Schikorski, T Schikorski, TA Nielsen, TG Allen, TG Banke, TG Oertner, TM Bartol Jr, V Burzomato, VA Levin, W Almers, W Lu, X Chen, XS Wu, Y Dehnes, Y Takumi, YH Huang, Z Nusser, Z Petrasek, Z Petrasek   +144 more
core   +2 more sources

Size stability and self-agglomeration of erythrocyte-derived membrane nanovesicles versus physiological extracellular vesicles [PDF]

arXiv, 2023
Extracellular vesicles (EVs) and plasma membrane-derived exosome-mimetic nanovesicles demonstrate significant potential for drug delivery. Latter synthetic provides higher throughput over physiological EVs. However they face size-stability and self-agglomeration challenges in physiological solutions to be properly characterized and addressed.
arxiv