Results 61 to 70 of about 210,770 (319)
Frontiers in Immunology, 2018 Gram-negative pathogens ubiquitously shed outer membrane vesicles (OMVs) that play a central role in initiating and regulating pathogenesis in the host.
Lorinda Turner +16 more
doaj +1 more source
Extracellular Vesicles in Renal Pathophysiology [PDF]
Frontiers in Molecular Biosciences, 2017 Extracellular vesicles are a heterogeneous population of microparticles released by virtually all living cells which have been recently widely investigated in different biological fields. They are typically composed of two primary types (exosomes and microvesicles) and are recently commanding increasing attention as mediators of cellular signaling ...
Pomatto, Margherita A. C. +3 more
openaire +5 more sources
Label-free single nanoparticle identification and characterization including infectious emergent virus [PDF]
, 2023 Screening of unknown particles, including viruses and nanoparticles, is key in medicine, industry and pollutant determination. However, existing techniques require sample a priori knowledge or modification (e.g. fluorescence). Here we introduce RYtov MIcroscopy for Nanoparticles Identification (RYMINI), a noninvasive and non-destructive optical ...
arxiv +1 more source
Extracellular vesicles and aging [PDF]
Stem Cell Investigation, 2017 Aging and the chronic diseases associated with aging place a tremendous burden on our healthcare system. As our world population ages dramatically over the next decades, this will only increase. Hence, there is a great need to discover fundamental mechanisms of aging to enable development of strategies for minimizing the impact of aging on our health ...
openaire +3 more sources
Frontiers in Endocrinology, 2021 Since the potential roles of extracellular vesicles secreted by adipose-derived mesenchymal stem cells (ADSCs) are not well understood in collagen metabolism, the purpose of this research was to evaluate the effects of ADSCs-extracellular vesicles in ...
Lu Wang +9 more
doaj +1 more source
Immunotherapeutic Potential of Extracellular Vesicles [PDF]
Frontiers in Immunology, 2014 Extracellular vesicle or EV is a term that encompasses all classes of secreted lipid membrane vesicles. Despite being scientific novelties, EVs are gaining importance as a mediator of important physiological and pathological intercellular activities possibly through the transfer of their cargo of protein and RNA between cells.
Ruenn Chai Lai +4 more
openaire +5 more sources
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
The riddle of the plant vacuolar sorting receptors [PDF]
Protoplasma 226 (12/2005) 103-8, 2006 Proteins synthesized on membrane-bound ribosomes are sorted at the Golgi apparatus level for delivery to various cellular destinations: the plasma membrane or the extracellular space, and the lytic vacuole or lysosome. Sorting involves the assembly of vesicles, which preferentially package soluble proteins with a common destination.
arxiv +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Comparative Study of Extracellular Vesicles from the Urine of Healthy Individuals and Prostate Cancer Patients. [PDF]
PLoS ONE, 2016 Recent studies suggest that extracellular vesicles may be the key to timely diagnosis and monitoring of genito-urological malignancies. In this study we investigated the composition and content of extracellular vesicles found in the urine of healthy ...
Olga E Bryzgunova +10 more
doaj +1 more source