Results 1 to 10 of about 190,111 (180)

Coordinated inheritance of extrachromosomal DNAs in cancer cells. [PDF]

Nature
The chromosomal theory of inheritance dictates that genes on the same chromosome segregate together while genes on different chromosomes assort independently1.
Hung KL, Jones MG, Wong IT, Curtis EJ, Lange JT, He BJ, Luebeck J, Schmargon R, Scanu E, Brückner L, Yan X, Li R, Gnanasekar A, Chamorro González R, Belk JA, Liu Z, Melillo B, Bafna V, Dörr JR, Werner B, Huang W, Cravatt BF, Henssen AG, Mischel PS, Chang HY.   +24 more
europepmc   +6 more sources

Coordinated inheritance of extrachromosomal DNA species in human cancer cells [PDF]

bioRxiv, 2023
The chromosomal theory of inheritance has dominated human genetics, including cancer genetics. Genes on the same chromosome segregate together while genes on different chromosomes assort independently, providing a fundamental tenet of Mendelian ...
Hung KL, Jones MG, Wong IT, Lange JT, Luebeck J, Scanu E, He BJ, Brückner L, Li R, González RC, Schmargon R, Dörr JR, Belk JA, Bafna V, Werner B, Huang W, Henssen AG, Mischel PS, Chang HY.   +18 more
europepmc   +5 more sources

Extrachromosomal inheritance in bacteria [PDF]

Bacteriological Reviews, 1969
INTRODUCTION............................................................ 211 Definitions.................................................................. 211 Overall Genetic Organization of aPlasmid.
Richard P. Novick
semanticscholar   +6 more sources

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma [PDF]

Nature Genetics, 2018
To understand how genomic heterogeneity of glioblastoma (GBM) contributes to poor therapy response, we performed DNA and RNA sequencing on GBM samples and the neurospheres and orthotopic xenograft models derived from them.
Ana C. deCarvalho, Hoon Kim, Laila Poisson, Mary E. Winn, Claudius Mueller, David Cherba, Julie Koeman, Sahil Seth, Alexei Protopopov, Michelle M. Felicella, Siyuan Zheng, Asha S. Multani, Yongying Jiang, Jianhua Zhang, Do‐Hyun Nam, Emanuel F. Petricoin, Lynda Chin, Tom Mikkelsen, Roel G.W. Verhaak   +18 more
semanticscholar   +8 more sources

EXTRACHROMOSOMAL INHERITANCE OF CARBON DIOXIDE SENSITIVITY IN THE MOSQUITO CULEX QUINQUEFASCIATUS [PDF]

Genetics, 1983
Mosquitoes from a laboratory colony of Culex quinquefasciatus from Matsu Island, China, develop irreversible paralytic symptoms after exposure to carbon dioxide at 1 degree.
Donald A. Shroyer, Léon Rosen
semanticscholar   +5 more sources

Reciprocal extrachromosomal inheritance in barley: the transmission of an infective element through male and female gametes

Suomen Maataloustieteellisen Seuran Tiedote
My backcross pollinations of 53 spontaneum barleys recurrently with cv. ‘Adorra’ resulted in a maternally inherited, partial spike fertility case assigned “58”.
Hannu Ahokas
semanticscholar   +5 more sources

Reciprocal extrachromosomal inheritance in rye (Secale cereale L.) [PDF]

Hereditas, 2009
In an inbred line of Steel rye (Stalrag), a chlorophyll mutant (status paralbomaculatus) arose spontaneously that displayed both extrachromosomal maternal and paternal inheritance in crosses.
SUNE FRÖST, LUDVIGS VAIVARS, Curt Carlbom   +2 more
semanticscholar   +4 more sources

Inheritance of extrachromosomal rDNA in Physarum polycephalum. [PDF]

Molecular and Cellular Biology, 1983
In the acellular slime mold Physarum polycephalum, the several hundred genes coding for rRNA are located on linear extrachromosomal DNA molecules of a discrete size, 60 kilobases. Each molecule contains two genes that are arranged in a palindromic fashion and separated by a central spacer region. We investigated how rDNA is inherited after meiosis. Two
Patrick J. Ferris, Volker M. Vogt, C L Truitt   +2 more
openalex   +4 more sources

Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast [PDF]

eLife, 2019
Production of healthy gametes in meiosis relies on the quality control and proper distribution of both nuclear and cytoplasmic contents. Meiotic differentiation naturally eliminates age-induced cellular damage by an unknown mechanism.
Grant A King, Jay S Goodman, Jennifer G Schick, Keerthana Chetlapalli, Danielle M Jorgens, Kent L McDonald, Elçin Ünal   +6 more
doaj   +4 more sources

GENE-23. DISCORDANT INHERITANCE OF CHROMOSOMAL AND EXTRACHROMOSOMAL DNA ELEMENTS CONTRIBUTE TO DYNAMIC DISEASE EVOLUTION IN GLIOBLASTOMA [PDF]

Neuro-Oncology, 2017
Ana C. deCarvalho, Hoon Kim, Laila Poisson, Julie Koeman, Tom Mikkelsen, Roel G.W. Verhaak   +5 more
semanticscholar   +4 more sources