Extrachromosomal elements in a super-suppression system of yeast I. A nuclear gene controlling the inheritance of the extrachromosomal elements [PDF]
Heredity, 1971 Extrachromosomal elements in a super-suppression system of yeast I.
C. S. H. Young, B. S. Cox
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Inheritance of extrachromosomal ribosomal DNA during the asexual life cycle of Dictyostelium discoideum: examination by use of DNA polymorphisms. [PDF]
Molecular and Cellular Biology, 1985 Wild-type isolates of Dictyostelium discoideum exhibited differences in the size of restriction fragments of the extrachromosomal 88-kilobase ribosomal DNA (rDNA) palindrome. Polymorphisms in rDNA also were found among strains derived solely from the NC4 wild-type isolate.
Dennis L. Welker +2 more
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Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis. [PDF]
PLoS PathogensIntegrative and conjugative elements (ICEs) play a vital role in bacterial evolution by carrying essential genes that confer adaptive functions to the host.
Qibing Gu +6 more
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Connecting the dots: Epigenetic regulation of extrachromosomal and inherited DNA amplifications. [PDF]
J Biol ChemDNA amplification has intrigued scientists for decades. Since its discovery, significant progress has been made in understanding the mechanisms promoting DNA amplification and their associated function(s). While DNA copy gains were once thought to be regulated purely by stochastic processes, recent findings have revealed the important role of ...
Azadegan C, Santoro J, Whetstine JR.
europepmc +3 more sources
Borg extrachromosomal elements of methane-oxidizing archaea have conserved and expressed genetic repertoires [PDF]
Nature CommunicationsBorgs are huge extrachromosomal elements (ECE) of anaerobic methane-consuming “Candidatus Methanoperedens” archaea. Here, we used nanopore sequencing to validate published complete genomes curated from short reads and to reconstruct new genomes.
Marie C. Schoelmerich +18 more
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Transcriptional immune suppression and up-regulation of double-stranded DNA damage and repair repertoires in ecDNA-containing tumors [PDF]
eLifeExtrachromosomal DNA is a common cause of oncogene amplification in cancer. The non-chromosomal inheritance of ecDNA enables tumors to rapidly evolve, contributing to treatment resistance and poor outcome for patients.
Miin S Lin +6 more
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Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma [PDF]
bioRxiv, 2016 Ana C. deCarvalho +18 more
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Extrachromosomal inheritance of oligomycin resistance in yeast
FEBS Letters, 1970 K. Wakabayashi, N. Gunge
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PlasmidHostFinder: Prediction of Plasmid Hosts Using Random Forest
mSystems, 2022 Plasmids play a major role facilitating the spread of antimicrobial resistance between bacteria. Understanding the host range and dissemination trajectories of plasmids is critical for surveillance and prevention of antimicrobial resistance ...
Derya Aytan-Aktug +8 more
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Circlehunter: a tool to identify extrachromosomal circular DNA from ATAC-Seq data
Oncogenesis, 2023 In cancer, extrachromosomal circular DNA (ecDNA), or megabase-pair amplified circular DNA, plays an essential role in intercellular heterogeneity and tumor cell revolution because of its non-Mendelian inheritance.
Manqiu Yang +4 more
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