Results 11 to 20 of about 2,768 (134)

Coordinated inheritance of extrachromosomal DNA species in human cancer cells [PDF]

open access: gold, 2023
ABSTRACTThe chromosomal theory of inheritance has dominated human genetics, including cancer genetics. Genes on the same chromosome segregate together while genes on different chromosomes assort independently, providing a fundamental tenet of Mendelian inheritance.
King L. Hung   +18 more
openalex   +3 more sources

Reciprocal extrachromosomal inheritance in rye (Secale cereale L.) [PDF]

open access: goldHereditas, 2009
In an inbred line of Steel rye (Stalrag), a chlorophyll mutant (status paralbomaculatus) arose spontaneously that displayed both extrachromosomal maternal and paternal inheritance in crosses. Striata plants gave rise to albino, striata, and normal offspring when selfed.
SUNE FRÖST   +2 more
openalex   +2 more sources

EXTRACHROMOSOMAL INHERITANCE OF CARBON DIOXIDE SENSITIVITY IN THE MOSQUITO CULEX QUINQUEFASCIATUS [PDF]

open access: bronzeGenetics, 1983
ABSTRACT Mosquitoes from a laboratory colony of Culex quinquefasciatus from Matsu Island, China, develop irreversible paralytic symptoms after exposure to carbon dioxide at 1°. This CO2 sensitivity is caused by an inherited infectious agent, probably a virus.
Donald A. Shroyer, Léon Rosen
openalex   +3 more sources

GENE-23. DISCORDANT INHERITANCE OF CHROMOSOMAL AND EXTRACHROMOSOMAL DNA ELEMENTS CONTRIBUTE TO DYNAMIC DISEASE EVOLUTION IN GLIOBLASTOMA [PDF]

open access: bronzeNeuro-Oncology, 2017
Ana C. deCarvalho   +5 more
openalex   +2 more sources

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma [PDF]

open access: greenNature Genetics, 2018
ABSTRACTTo understand how genomic heterogeneity of glioblastoma (GBM) contributes to the poor response to therapy, which is characteristic of this disease, we performed DNA and RNA sequencing on GBM tumor samples and the neurospheres and orthotopic xenograft models derived from them.
Ana C. deCarvalho   +18 more
openalex   +6 more sources

Connecting the dots: Epigenetic regulation of extrachromosomal and inherited DNA amplifications. [PDF]

open access: yesJ Biol Chem
DNA amplification has intrigued scientists for decades. Since its discovery, significant progress has been made in understanding the mechanisms promoting DNA amplification and their associated function(s). While DNA copy gains were once thought to be regulated purely by stochastic processes, recent findings have revealed the important role of ...
Azadegan C, Santoro J, Whetstine JR.
europepmc   +3 more sources

EXPERIMENTAL ANALYSIS OF A PATERNALLY INHERITED EXTRACHROMOSOMAL FACTOR [PDF]

open access: yesGenetics, 1986
ABSTRACT Virtually all known cases of extrachromosomal inheritance involve cytoplasmic inheritance through the maternal line. Recently, a paternally transmitted factor that causes the production of all-male families has been discovered in a parasitic wasp.
J H, Werren, J, van den Assem
openaire   +2 more sources

Sperm-Mediated Transgenerational Inheritance

open access: yesFrontiers in Microbiology, 2017
Spermatozoa of virtually all species can spontaneously take up exogenous DNA or RNA molecules and internalize them into nuclei. In this article I review evidence for a key role of a reverse transcriptase (RT) activity, encoded by LINE-1 retrotransposons,
Corrado Spadafora
doaj   +1 more source

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