Essential Genetic Interactors of SIR2 Required for Spatial Sequestration and Asymmetrical Inheritance of Protein Aggregates [PDF]
, 2014 Sir2 is a central regulator of yeast aging and its deficiency increases daughter cell inheritance of stress-and aging-induced misfolded proteins deposited in aggregates and inclusion bodies.
Cvijovic, Marija +12 more
core +6 more sources
EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA
iScience, 2019 Summary: Oncogene amplification is one of the most common drivers of genetic events in cancer, potently promoting tumor development, growth, and progression.
Utkrisht Rajkumar +6 more
doaj
Engineering recombinant orsay virus directly in the metazoan host Caenorhabditis elegans [PDF]
, 2014 The recent identification of Orsay virus, the first virus that is capable of naturally infecting Caenorhabditis elegans, provides a unique opportunity to explore host-virus interaction studies in this invaluable model organism.
Franz, Carl J +2 more
core +2 more sources
Heritable genome editing in C. elegans via a CRISPR-Cas9 system [PDF]
, 2014 CRISPR-Cas systems have been used with single-guide RNAs for accurate gene disruption and conversion in multiple biological systems. Here we report the use of the endonuclease Cas9 to target genomic sequences in the C.
Calarco, John A. +5 more
core +1 more source
Crossovers between epigenesis and epigenetics. A multicenter approach to the history of epigenetics (1901-1975) [PDF]
, 2014 The origin of epigenetics has been traditionally traced back to Conrad Hal Waddington's foundational work in 1940s. The aim of the present paper is to reveal a hidden history of epigenetics, by means of a multicenter approach.
Costa, R., Frezza, G.
core
Microtubule-dependent ribosome localization in C. elegans neurons. [PDF]
, 2017 Subcellular localization of ribosomes defines the location and capacity for protein synthesis. Methods for in vivo visualizing ribosomes in multicellular organisms are desirable in mechanistic investigations of the cell biology of ribosome dynamics. Here,
Ellisman, Mark H +3 more
core +1 more source
DNA Synthesis, Methylation and Degradation During Conjugation in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]
, 1985 We have investigated the timing of DNA synthesis, methylation and degradation during macronuclear development in the ciliate, Tetrahymena thermophila. DNA synthesis was first detected in the anlagen early in macronuclear development, but the majority of ...
Harrison, Gail Singer +1 more
core +1 more source
[Bacterial resistance to antibiotics by extrachromosomal inheritance].
Revista medica de Chile, 1973 Felipe C. Cabello, Silva Ab
openalex +2 more sources
Body Perception: Intersensory Origins of Self and Other Perception in Newborns [PDF]
, 2010 SummarySelf-perception involves integrating changes in visual, tactile, and proprioceptive stimulation from self-motion and discriminating these changes from those of other objects.
Bahrick, L.E.
core +3 more sources
Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae [PDF]
, 2020 © The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research. Circular DNA can arise from all parts of eukaryotic chromosomes. In yeast, circular ribosomal DNA (rDNA) accumulates dramatically as cells age, however little
Alizadeh, Sefa +8 more
core +1 more source