Results 41 to 50 of about 2,768 (134)

Cas9‐Rep fusion tethers donor DNA in vivo and boosts the efficiency of HDR‐mediated genome editing

Plant Biotechnology Journal, Volume 23, Issue 6, Page 2006-2017, June 2025.
Summary Genome editing based on the homology‐directed repair (HDR) pathway enables scar‐free and precise genetic manipulations. However, the low frequency of HDR hinders its application in plant genome editing. In this study, we engineered the fusion of Cas9 and a viral replication protein (Rep) as a molecular bridge to tether donor DNA in vivo, which ...
Zhentao Zhou, Jiahui Xiao, Shuai Yin, Yache Chen, Yang Yuan, Jianwei Zhang, Lizhong Xiong, Kabin Xie   +7 more
wiley   +1 more source

Assessing Human Ribosomal DNA Variation and Its Association With Phenotypic Outcomes

BioEssays, Volume 47, Issue 4, April 2025.
Genetic variation within the multi‐copy, multi‐locus ribosomal DNA (rDNA) can contribute to human complex trait variability. This variation takes the form of copy number, structural arrangement, and sequence differences. This review summarizes what is currently known about human rDNA variation, its causes, and its association with phenotypic outcomes ...
Francisco Rodriguez‐Algarra, Elliott Whittaker, Sandra del Castillo del Rio, Vardhman K. Rakyan   +3 more
wiley   +1 more source

Decision letter for "Can non‐Mendelian inheritance of extrachromosomal circular DNA‐mediated EPSPS gene amplification provide an opportunity to reverse resistance to glyphosate?"

, 2021

openalex   +2 more sources

Review for "Can non‐Mendelian inheritance of extrachromosomal circular DNA‐mediated EPSPS gene amplification provide an opportunity to reverse resistance to glyphosate?"

, 2020
Martín M. Vila‐Aiub
openalex   +2 more sources

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma [PDF]

, 2016
Ana C. deCarvalho, Hoon Kim, Laila Poisson, Mary E. Winn, Claudius Mueller, David Cherba, Julie Koeman, Sahil Seth, Alexei Protopopov, Michelle M. Felicella, Siyuan Zheng, Asha S. Multani, Yongying Jiang, Jianhua Zhang, Do‐Hyun Nam, Emanuel F. Petricoin, Lynda Chin, Tom Mikkelsen, Roel G.W. Verhaak   +18 more
openalex   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

Decision letter for "Can non‐Mendelian inheritance of extrachromosomal circular DNA‐mediated EPSPS gene amplification provide an opportunity to reverse resistance to glyphosate?"

, 2020

openalex   +1 more source

Extrachromosomal inheritance of oligomycin resistance in yeast

FEBS Letters, 1970
Wakabayashi, K., Gunge, N.
openaire   +2 more sources

Inheritance of Extrachromosomal rDNA in Physarum polycephalum

, 1983
Patrick Ferris, Volker M. Vogt, Christine L. Truitt   +2 more
openalex   +2 more sources