Results 41 to 50 of about 192,718 (174)

Piwi mutant germ cells transmit a form of heritable stress that promotes longevity

open access: yesAging Cell, Volume 24, Issue 1, January 2025.
prg‐1/Piwi mutants with strongly reduced fertility live long, and longevity is transmitted for one generation of cross‐progeny. Stress granules are increased for long‐lived Piwi mutants and their progeny. Loss of DAF‐16 stress response transcription factor or DCAP‐1 stress granule protein causes very short life for moderately or strongly reduced ...
Bree Heestand   +5 more
wiley   +1 more source

EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA

open access: yesiScience, 2019
Summary: Oncogene amplification is one of the most common drivers of genetic events in cancer, potently promoting tumor development, growth, and progression.
Utkrisht Rajkumar   +6 more
doaj  

First report of glyphosate resistance in an Amaranthus palmeri population from Europe

open access: yesWeed Research, Volume 65, Issue 1, January/February 2025.
Abstract The invasive weed Amaranthus palmeri is spreading throughout Spain, with Catalonia being one of the most affected regions. For this species, acetolactate synthase‐inhibiting herbicide‐resistant populations have been reported, and now glyphosate resistance is also suspected.
Alfredo Manicardi   +7 more
wiley   +1 more source

Antibiotics and Antimicrobial Resistance Genes in a Gut Microbiota as a Reservoir—A Review

open access: yesAdvanced Gut &Microbiome Research, Volume 2025, Issue 1, 2025.
The human microbiota is one of the most powerful sites for antibiotic resistance (AR) genes. It is home to thousands of microbes at various stages of development. The complex inner environment has the potential to affect the host’s immunity, metabolism, and genetic makeup. The gut microbiota has an incredibly high level of gene diversity.
Bismark Dabuo   +4 more
wiley   +1 more source

AAV‐mediated Gene Therapy for Hereditary Deafness: Progress and Perspectives

open access: yesAdvanced Science, Volume 11, Issue 47, December 18, 2024.
Gene therapy has successfully restored hearing function in hereditary autosomal recessive deafness 9 (DFNB9) caused by the OTOFERLIN (OTOF) mutation, providing a translational paradigm for gene therapy in other forms of genetic deafness. In this work, a systematic overview of the current state of gene therapy for hereditary deafness, with particular ...
Liyan Zhang   +14 more
wiley   +1 more source

Genetic Analysis of 17q Terminal Partial Trisomy

open access: yesClinical Case Reports, Volume 12, Issue 12, December 2024.
ABSTRACT Chromosomal trisomy syndrome is associated with diverse clinical phenotypes, including intellectual disability. Partial trisomy of the distal 17q is a rare anomaly with similar clinical features, including psychomotor and growth deficits, facial dysmorphism, and microcephaly.
Huiling Zheng   +6 more
wiley   +1 more source

Problems of Inheritance at Java Inner Class [PDF]

open access: yesarXiv, 2013
Single inheritance has been widely accepted in the current programming practice to avoid the complication that incurred by multiple inheritance. Single inheritance enhances the reusability of codes and eliminates the confusion of identical methods that possibly defined in two superclasses.
arxiv  

Generalized Inheritance [PDF]

open access: yesarXiv, 2015
Generalized inheritance is used with the almost-conformal Killing equation. Examples are the flat FRW, Kasner, and deSitter metrics. The volume changes in FRW while transitioning to a stiff fluid are discussed.
arxiv  

Curvature bounds on length-minimizing discs [PDF]

open access: yesarXiv, 2023
We show that a length-minimizing disk inherites the upper curvature bound of the target. As a consequence we prove that harmonic discs and ruled discs inherit the upper curvature bound from the ambient space.
arxiv  

Overexpression of mitochondrial fission or mitochondrial fusion genes enhances resilience and extends longevity

open access: yesAging Cell, Volume 23, Issue 10, October 2024.
Overexpression of mitochondrial fission genes or mitochondrial fusion genes both result in mitochondrial fragmentation, increased resilience, and extended longevity. Overexpression of mitochondrial fusion genes activates multiple pathways of cellular resilience, some of which are required for their extended longevity.
Annika Traa   +7 more
wiley   +1 more source

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