Results 41 to 50 of about 1,654,064 (188)

Extracorporeal CO2 removal from 1977 to 2014

, 2015
Introduction. Extracorporeal CO2 removal, and extracorporeal oxygenation, in veno-venous bypass, are forms of respiratory support aiming at buying time during the cure of the causative disease. Description of review.
L. Gattinoni
core   +2 more sources

A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenation

Intensive Care Medicine Experimental, 2018
Background Venovenous extracorporeal membrane oxygenation (vv-ECMO) is an effective treatment for severe respiratory failure. The interaction between the cardiorespiratory system and the oxygenator can be explored with mathematical models.
Christopher John Joyce, Kiran Shekar, David Andrew Cook   +2 more
doaj   +1 more source

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

Hemolysis at low blood flow rates: in-vitro and in-silico evaluation of a centrifugal blood pump

Journal of Translational Medicine, 2021
Background Treating severe forms of the acute respiratory distress syndrome and cardiac failure, extracorporeal membrane oxygenation (ECMO) has become an established therapeutic option.
Malte Schöps, Sascha H. Groß-Hardt, Thomas Schmitz-Rode, Ulrich Steinseifer, Daniel Brodie, Johanna C. Clauser, Christian Karagiannidis   +6 more
doaj   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Size of cannula for extracorporeal CO2 removal therapies [PDF]

, 2015
Extracorporeal CO2 removal devices (ECCO2R) can be used in clinics to decarboxylate blood externally for patients suffering from pulmonary insufficiencies like acute respiratory distress syndrome.
Dauby, Pierre, Habran, Simon, MORIMONT, Philippe, Desaive, Thomas, LAMBERMONT, Bernard   +4 more
core   +1 more source

ECCO2R therapy in the ICU: consensus of a European round table meeting

Critical Care, 2020
Background With recent advances in technology, patients with acute respiratory distress syndrome (ARDS) and severe acute exacerbations of chronic obstructive pulmonary disease (ae-COPD) could benefit from extracorporeal CO2 removal (ECCO2R).
Alain Combes, Georg Auzinger, Gilles Capellier, Damien du Cheyron, Ian Clement, Guglielmo Consales, Wojciech Dabrowski, David De Bels, Francisco Javier González de Molina Ortiz, Antje Gottschalk, Matthias P. Hilty, David Pestaña, Eduardo Sousa, Redmond Tully, Jacques Goldstein, Kai Harenski   +15 more
doaj   +1 more source

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

Advanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi, Yu‐Hui Gu, Kai‐Wen Ren, Xiao‐Hong Yu, Yun‐Long Xia, Xiao‐Lei Yang, Hui‐Hua Li   +6 more
wiley   +1 more source

Systematic review and meta-analysis of complications and mortality of veno-venous extracorporeal membrane oxygenation for refractory acute respiratory distress syndrome

Annals of Intensive Care, 2017
Veno-venous extracorporeal membrane oxygenation (ECMO) for refractory acute respiratory distress syndrome (ARDS) is a rapidly expanding technique. We performed a systematic review and meta-analysis of the most recent literature to analyse complications ...
Sergi Vaquer, Candelaria de Haro, Paula Peruga, Joan Carles Oliva, Antonio Artigas   +4 more
doaj   +1 more source

Effects of Extracorporeal Shock Wave Therapy on Tendon Integrity, Biomechanical Strength, Matrix Remodeling, Inflammation, Angiogenesis, and Tenogenic Differentiation in Rotator Cuff Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Extracorporeal shock wave therapy (ESWT) improves tendon‐bone healing after rotator cuff injury (RCI), but its underlying cellular mechanisms remain unknown. This study aimed to explore the therapeutic effects of ESWT on RCI, with a particular focus on endothelial cells and tenocytes.
Hua Wang, Fei Wu, Jia‐Qing Miao
wiley   +1 more source