Results 81 to 90 of about 5,879 (176)
Uveal melanoma: Estimating prognosis
Uveal melanoma is the most common primary malignant tumor of the eye in adults, predominantly found in Caucasians. Local tumor control of uveal melanoma is excellent, yet this malignancy is associated with relatively high mortality secondary to ...
Swathi Kaliki +2 more
doaj +1 more source
Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling +6 more
wiley +1 more source
ABSTRACT Objective Older Aboriginal and Torres Strait Islander Australians are central to their communities, providing cultural leadership and care. However, colonisation and systemic inequities have led to significant health disparities, with chronic diseases and dementia disproportionately affecting those aged over the age of 55 years.
Rachel Quigley +11 more
wiley +1 more source
Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen +9 more
wiley +1 more source
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du +11 more
wiley +1 more source
Bilateral IgG4‐Related Dacryoadenitis
ABSTRACT Chronic dacryoadenitis is an uncommon inflammation of the lacrimal gland that may have various etiologies with similar presentations. IgG4‐related ophthalmic disease most often manifests as painless lacrimal gland enlargement, so the clinicians should consider IgG4‐related disease as a diagnostic possibility for dacryoadenitis.
Yan Song, Lin Ding, Tao Shen
wiley +1 more source
ABSTRACT Ocular trauma in children is an important cause of avoidable visual morbidity, with potential psychosocial, educational, and quality‐of‐life consequences. Domestic spring door closers, commonly called “trapdoor springs” in Ghana, may cause significant periocular injury when an exposed hook is accidentally encountered; however, this mechanism ...
Mac‐Cauley Harrison +13 more
wiley +1 more source
ABSTRACT Background and Aims Armed conflict in Sudan has severely disrupted traditional medical education, prompting a shift toward online learning as an alternative. While digital platforms enable educational continuity, they are associated with increased screen exposure and a rising incidence of digital eye strain (DES) among medical students.
Moram Elfadel Abdelrhaman Gasmalha +11 more
wiley +1 more source
Spatial multi‐omics of the mouse ocular globe after retinal ischemia‐reperfusion (RIR) injury identifies the ganglion cell layer (GCL) as an immunometabolic niche where Trem2+ microglia closely associate with stressed retinal ganglion cells (RGCs) through Trem2‐Apoe signaling.
Yunhong Shi +12 more
wiley +1 more source

