Results 81 to 90 of about 5,879 (176)

Uveal melanoma: Estimating prognosis

open access: yesIndian Journal of Ophthalmology, 2015
Uveal melanoma is the most common primary malignant tumor of the eye in adults, predominantly found in Caucasians. Local tumor control of uveal melanoma is excellent, yet this malignancy is associated with relatively high mortality secondary to ...
Swathi Kaliki   +2 more
doaj   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

open access: yesPROTEOMICS, Volume 26, Issue 9, Page 6-23, September 2026.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling   +6 more
wiley   +1 more source

The Development of a Framework to Support Ageing Well in the Torres Strait and Northern Peninsula Area of Australia

open access: yesAustralasian Journal on Ageing, Volume 45, Issue 3, September 2026.
ABSTRACT Objective Older Aboriginal and Torres Strait Islander Australians are central to their communities, providing cultural leadership and care. However, colonisation and systemic inequities have led to significant health disparities, with chronic diseases and dementia disproportionately affecting those aged over the age of 55 years.
Rachel Quigley   +11 more
wiley   +1 more source

Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy

open access: yesClinical Genetics, Volume 110, Issue 3, Page 336-346, September 2026.
Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen   +9 more
wiley   +1 more source

Idiopathic Orbital Inflammation Masquerading as Relapse of Seronegative Juvenile Myasthenia Gravis: A Case Report

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Wenhao Duan   +4 more
wiley   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, Volume 13, Issue 47, 24 August 2026.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

Bilateral IgG4‐Related Dacryoadenitis

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Chronic dacryoadenitis is an uncommon inflammation of the lacrimal gland that may have various etiologies with similar presentations. IgG4‐related ophthalmic disease most often manifests as painless lacrimal gland enlargement, so the clinicians should consider IgG4‐related disease as a diagnostic possibility for dacryoadenitis.
Yan Song, Lin Ding, Tao Shen
wiley   +1 more source

Spring Door Closer Entrapment of the Upper Eyelid: A Pediatric Periocular Foreign‐Body Injury With a Favorable Functional Outcome—A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Ocular trauma in children is an important cause of avoidable visual morbidity, with potential psychosocial, educational, and quality‐of‐life consequences. Domestic spring door closers, commonly called “trapdoor springs” in Ghana, may cause significant periocular injury when an exposed hook is accidentally encountered; however, this mechanism ...
Mac‐Cauley Harrison   +13 more
wiley   +1 more source

Prevalence of Digital Eye Strain Symptoms Among Sudanese Medical Students During Conflict‐Induced Online Learning: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Armed conflict in Sudan has severely disrupted traditional medical education, prompting a shift toward online learning as an alternative. While digital platforms enable educational continuity, they are associated with increased screen exposure and a rising incidence of digital eye strain (DES) among medical students.
Moram Elfadel Abdelrhaman Gasmalha   +11 more
wiley   +1 more source

Spatial multi‐omics unveils sphingolipid metabolic reprogramming within the retinal pathological niche

open access: yesiMeta, Volume 5, Issue 4, August 2026.
Spatial multi‐omics of the mouse ocular globe after retinal ischemia‐reperfusion (RIR) injury identifies the ganglion cell layer (GCL) as an immunometabolic niche where Trem2+ microglia closely associate with stressed retinal ganglion cells (RGCs) through Trem2‐Apoe signaling.
Yunhong Shi   +12 more
wiley   +1 more source

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