Results 131 to 140 of about 34,294 (314)

Quantifying the Single‐Cell Morphological Landscape of Cellular Transdifferentiation through Force Field Reconstruction

open access: yesAdvanced Science, EarlyView.
This study reconstructs the driving force field of fibroblast‐to‐neuron transdifferentiation from sparse single‐cell images by decomposing it into flux and time‐dependent potential gradient, extending the landscape‐flux framework to non‐steady‐state systems.
Chudan Yu   +3 more
wiley   +1 more source

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li   +19 more
wiley   +1 more source

Grow p‐type MoS2 on FeNC for CO2 Sensing in Complex Environments with Intelligent Recognition

open access: yesAdvanced Science, EarlyView.
In situ growth of p‐type MoS2 (p‐MoS2) on N‐ and Fe‐enriched carbon (FeNC) nanosheets allows for detection of carbon dioxide (CO2) fluctuation levels as low as 50 ppm at 25 °C. The induced S vacancies (Svacs) and the modulated electron distribution jointly improved sensing selectivity to CO2. Abstract A wealth of theoretical studies demonstrates p‐type
Yuefeng Gu   +8 more
wiley   +1 more source

Sombor topological indices for different nanostructures. [PDF]

open access: yesHeliyon, 2023
Imran M   +4 more
europepmc   +1 more source

Brillouin Microscopy of Breast tumor Spheroids On‐a‐Chip: Mechanical and Transcriptional Responses to Microfluidic‐Induced Rapid Deformations

open access: yesAdvanced Science, EarlyView.
Brillouin‐Raman Microspectroscopy on‐a‐Chip (BRmS) enables real‐time analysis of breast tumor spheroids in microfluidic channels. Following cyclical deformations, MCF10.DCIS.com spheroids are captured in recovery traps and imaged with BRmS. The applied deformations trigger a stiffening response marked by increased frequency shifts, elevation of the ...
Mona Makkieh   +22 more
wiley   +1 more source

Structural Variation and 3D Genome‐Driven DNA/RNA Methylation Divergence Contributing to Cotton Fiber Domestication

open access: yesAdvanced Science, EarlyView.
These findings elucidated the crucial role of the “SVs‐3D genome remodeling‐epigenetic modifications‐gene expression” cascade regulatory network in cotton fiber domestication, offering both a theoretical foundation and genetic resources for molecular design breeding in fiber crops.
Lei Shao   +11 more
wiley   +1 more source

Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk

open access: yesAdvanced Science, EarlyView.
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu   +10 more
wiley   +1 more source

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