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The status of eye irritancy testing: a regulatory perspective.
Lens and eye toxicity research, 1993Eye irritation testing is a salient public issue and continues to escalate on the public agenda. Issues relevant to this milieu include legislative proposals to ban animal use for cosmetic testing, adequacy of the current standard (viz., the Draize Eye Irritancy Test), availability of non-animal methodologies, validation paradigm for new testing models,
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HET-CAM test for determining the possible eye irritancy of pesticides
Acta Veterinaria Hungarica, 2010Agrochemicals and veterinary products must undergo numerous toxicological tests before registration. The use of animals in these studies is a controversial issue. The Draize eye irritation test is one of the most criticised methods because of the injuries inflicted on the test animals.
Budai, Péter +3 more
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In vitro alternatives to the draize eye irritation test
Journal of Toxicology: Cutaneous and Ocular Toxicology, 1989AbstractThe Joint Government-Industry Workshop on Progress Towards Non-Animal Alternatives to the Draize Test was organized to provide a forum for the discussion of issues involved in the regulatory acceptance of data from alternative tests and for the discussion of recent progress towards that end.
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[In vitro alternatives to Draize eye irritation test].
Wei sheng yan jiu = Journal of hygiene research, 2006For reasons of animal welfare and better science, a series of in vitro methods, including assays based isolated eye or cornea, Chorioallantoic membrane, cultured tissue or cell, had been established and evaluated to replace the Draize eye irritation test.
Jianchang, Zhou +3 more
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Human-relevant approaches to assess eye corrosion/irritation potential of agrochemical formulations
Cutaneous and Ocular Toxicology, 2021Amy J Clippinger, , Nicole Kleinstreuer
exaly
Ophthalmologic Perspectives on Eye Irritation Testing
Journal of Toxicology: Cutaneous and Ocular Toxicology, 1998B. Nussenblatt Robert +6 more
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Skin and Eye Irritation Tests on Hexanol
Journal of the American College of Toxicology, 1992Guido A. Jacobs, Mark A. Martens
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