Protein Trafficking Through the Eye of the Fly
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Identification of Brimonidine as a Novel Substrate of Organic Cation Transporters OCT2 and MATE1 Expressed in Human Eye. [PDF]
Kölz C +7 more
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Gap junction-mediated signaling coordinates Rhodopsin coupling for Drosophila color vision. [PDF]
Zhang X +4 more
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A preliminary study developing a scoring model incorporating fibrinogen-like protein 2 for predicting glucocorticoid resistance in thyroid eye disease. [PDF]
Matsuzawa K +11 more
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From pineal photoreception to optogenetics: functional colour opponency based on a pineal bistable opsin. [PDF]
Wada S +3 more
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Protein and polypeptide mediated delivery to the eye
Advanced Drug Delivery Reviews, 2022Hybrid or recombinant protein-polymers, peptide-based biomaterials, and antibody-targeted therapeutics are widely explored for various ocular conditions and vision correction. They have been noted for their potential biocompatibility, potency, adaptability, and opportunities for sustained drug delivery. Unique to peptide and protein therapeutics, their
Sara Aly, Attia, J Andrew, MacKay
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Pax proteins and eye development
Current Opinion in Neurobiology, 1996Homologous members of the Pax gene family are required for eye development in Drosophila and vertebrates. Despite superficial similarities in the phenotypes of vertebrates with mutations in pax-6 and Drosophila eyeless mutants, it remains uncertain whether the two proteins encoded by these genes have comparable functions.
R, Macdonald, S W, Wilson
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A novel Eyes Absent 2 protein is expressed in the human eye
Gene, 2002The Drosophila eyes absent (eya) gene has a role in regulating cell death and/or differentiation and is expressed throughout development. We evaluated the transcripts and proteins encoded by one of the human homologues of Drosophila eya coined Eyes Absent 2 (EYA2).
Brian E, Fee +2 more
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A ligand's-eye view of protein similarity
Nature Methods, 2013Classification of proteins by ligand binding similarity offers an alternative approach to evolutionary methods for organizing and understanding biology, allowing new insights into protein function and physiological signal transduction.
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Dityrosine formation in the proteins of the eye lens
Current Eye Research, 1992The presence of dityrosine crosslinks in the proteins of the lens is a subject of some debate. We have investigated the formation of dityrosine in the lens proteins, the crystallins, through reactions mediated by reactive oxygen species, as well as through direct photolysis of proteins in the UVB region.
P, Guptasarma, D, Balasubramanian
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