Results 1 to 10 of about 79,142 (299)

Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases

, 2012
Arylstibonates structurally resemble phosphotyrosine side chains in proteins and here we addressed the ability of such compounds to act as inhibitors of a panel of mammalian tyrosine and dual-specificity phosphatases. Two arylstibonates both possessing a
Andersen, Boutros, Burke, Claire Scott, David J. Mann, Doman, Gasparotto, Gillian F. Whyte, Huyer, James Stivers, Jessica Knott, Katherine A. Scott, Kim, Kotoris, Kristjansdottir, Lok Hang Mak, Oscar Ces, Pagliarini, Picha, Rosivatz, Rudiger Woscholski, Rudolph, Schmid, Schmid, Seiple, Tonks, Vintonyak, Whisstock, Yu Ye   +28 more
core   +1 more source

Fyn-Mediated Regulation of Protein Kinase A [PDF]

, 2017
Protein kinases are enzymes important for signal transduction in the regulation of cellular processes. The cAMP-dependent protein kinase A (PKA) has been previously reported to regulate the activity of the Src family kinase Fyn, an event important for ...
Barritt, Sam
core   +1 more source

Phospho‐Proteomics Identifies D‐Group MAP Kinases as Substrates of the Arabidopsis Tyrosine Phosphatase RLPH2

Plant Direct
Despite being one of the few bona fide plant tyrosine phosphatases, the Arabidopsis thaliana Rhizobiales‐like phosphatase 2 (RLPH2) has no known substrates.
Anne‐Marie Labandera, Ryan Toth, Sierra Mitchell, Jayde J. Johnson, Brooklyn Kurucz, Juliette Puyaubert, Emmanuel Baudouin, R. Glen Uhrig, Greg B. Moorhead   +8 more
doaj   +1 more source

Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow. [PDF]

IUBMB Life, 2023
Tonks NK.
europepmc   +1 more source

Mapping the Chemical Space of Active-Site Targeted Covalent Ligands for Protein Tyrosine Phosphatases. [PDF]

Chembiochem, 2023
Hong SH, Xi SY, Johns AC, Tang LC, Li A, Hum MN, Chartier CA, Jovanovic M, Shah NH.   +8 more
europepmc   +1 more source

Competition and cooperation among receptor tyrosine phosphatases control motoneuron growth cone guidance in Drosophila [PDF]

, 1997
The neural receptor tyrosine phosphatases DPTP69D, DPTP99A and DLAR are involved in motor axon guidance in the Drosophila embryo. Here we analyze the requirements for these three phosphatases in growth cone guidance decisions along the ISN and SNb ...
Desai, Chand J., Krueger, Neil X., Saito, Haruo, Zinn, Kai   +3 more
core  

Roles of protein tyrosine phosphatases in hepatocellular carcinoma progression (Review). [PDF]

Oncol Rep, 2023
Chen YL, Hsieh CC, Chu PM, Chen JY, Huang YC, Chen CY.   +5 more
europepmc   +1 more source

Methyl Syringate Stimulates Glucose Uptake by Inhibiting Protein Tyrosine Phosphatases Relevant to Insulin Resistance. [PDF]

Life (Basel), 2023
Ahn D, Kwon J, Song S, Lee J, Yoon S, Chung SJ.   +5 more
europepmc   +1 more source

Correction to "Loop Dynamics and Enzyme Catalysis in Protein Tyrosine Phosphatases". [PDF]

J Am Chem Soc, 2022
Crean RM, Biler M, Corbella M, Calixto AR, van der Kamp MW, Hengge AC, Kamerlin SCL.   +6 more
europepmc   +1 more source

Synthesis of small peptide compounds, molecular docking, and inhibitory activity evaluation against phosphatases PTP1B and SHP2

Drug Design, Development and Therapy, 2018
Tomasz Kostrzewa,1 Kamlesh K Sahu,2 Magdalena Gorska-Ponikowska,1 Jack A Tuszynski,3 Alicja Kuban-Jankowska1 1Department of Medical Chemistry, Medical University of Gdansk, Gdansk, Poland; 2Department of Medical Microbiology and Immunology, University ...
Kostrzewa T, Sahu KK, Gorska-Ponikowska M, Tuszynski JA, Kuban-Jankowska A   +4 more
doaj