Results 161 to 170 of about 441,178 (207)
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A ligand’s-eye view of protein binding
Journal of Computer-Aided Molecular Design, 2008Docking tools created for structure-based design and virtual screening have also been used to automate ligand alignment for comparative molecular field analysis (CoMFA). Models based on such alignments have been compared with those obtained based solely on shared ligand substructures, but such comparisons have generally failed to distinguish between ...
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Some problems of protein chemistry of the eye
Documenta Ophthalmologica, 1951Proteins are substances on which the organic composition and structure of the cell depends. The protein concentration of the crystallin lens is higher than that of any other organ of the body. This predominance of proteins in the lens' substance points clearly towards the cardinal role they play in the metabolism of this organ.
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An Eye-Opener to Protein Structures
Complexus, 2002During the last 30 years of protein research, the main emphasis has been given to crystallographic details, while the very basics of polymer statistics have largely been ignored. This has resulted in a major detail being overlooked: the closed loops of the size dictated by the polypeptide chain flexibility, of which the globular proteins are actually ...
Igor N. Berezovsky +3 more
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A.M.A. Archives of Ophthalmology, 1954
OF THE proteins which are present in the vitreous body, the gelatinous material seems to be most significant. It has been termed vitrein,1or residual protein,2and a recent preparation of the structural protein has been called vitrosin.2Krause1purified the protein by filtration, followed by treatment with papain, and recorded some data on its chemical ...
R G, YOUNG, H H, WILLIAMS
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OF THE proteins which are present in the vitreous body, the gelatinous material seems to be most significant. It has been termed vitrein,1or residual protein,2and a recent preparation of the structural protein has been called vitrosin.2Krause1purified the protein by filtration, followed by treatment with papain, and recorded some data on its chemical ...
R G, YOUNG, H H, WILLIAMS
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Protein-Eye View of the in Meso Crystallization Mechanism
Langmuir, 2019For evolving biological and biomedical applications of hybrid protein?lipid materials, understanding the behavior of the protein within the lipid mesophase is crucial. After more than two decades since the invention of the in meso crystallization method, a protein-eye view of its mechanism is still lacking.
Leonie van ‘t Hag +15 more
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Software eyes for protein post‐translational modifications
Mass Spectrometry Reviews, 2014Post‐translational modifications (PTMs) are critical to almost all aspects of complex processes of the cell. Identification of PTMs is one of the biggest challenges for proteomics, and there have been many computational studies for the analysis of PTMs from tandem mass spectrometry (MS/MS).
Seungjin, Na, Eunok, Paek
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Proteins in tears from healthy and diseased eyes
Documenta Ophthalmologica, 1980The levels of total protein in tears from healthy donors, conjunctivitis vernalis patients, and conjunctivitis follicularis patients, were 625, 1370 and 1160 mg% respectively. Serum albumin accounted for 3.3%, 43% and 67% of the total protein of tears from these groups, and the level of proteins probably synthesized by the lacrimal gland, was in tears ...
A, Zavaro +3 more
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Serotonin induced protein phosphorylation in the aplysia eye
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1987Serotonin (5-HT) increases the phosphorylation of two low molecular weight phosphoproteins of 23,000 and 15,000 daltons molecular weight and decreases the phosphorylation of a 20,000 dalton phosphoprotein in the isolated Aplysia eye. The cAMP analog 8-benzylthio cAMP increases and decreases the phosphorylation of the 23,000 and 20,000 dalton 5-HT ...
D P, Lotshaw, J W, Jacklet
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Aqueous Humor Protein and Complement in Pseudophakic Eyes
Cornea, 1990Intraocular lens (IOL) insertion is now the standard method of aphakic correction in this country. Previous studies have shown that an IOL can activate the alternative complement system of normal human serum in vitro, thereby generating peptides capable of stimulating inflammation that can result in visual morbidity in pseudophakic eyes.
A W, Tuberville, T O, Wood
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Catecholamine and protein synthesis in the eyes of Aplysia californica
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1977Abstract 1. 1. The eyes of Aplysia californica were studied for their ability to synthesize proteins and catecholamines. 2. 2. Using high voltage electrophoresis two peaks which co-migrate with dopa and dopamine incorporated 14C tyrosine, suggesting dopamine as a putative neurotransmitter in the eye. 3. 3.
Y P, Loh, J W, Jacklet
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