Results 101 to 110 of about 27,592 (211)

Safety of anagliptin/metformin combination tablets evaluated by non‐inferiority between pre‐ and post‐serum lactic acid levels in Japanese patients with type 2 diabetes and moderate renal impairment (AMELIO STUDY)

Journal of Diabetes Investigation, Volume 17, Issue 4, Page 636-648, April 2026.
To investigate the safety of anagliptin/metformin combination tablets in Japanese patients of type 2 diabetes with moderate renal impairment. This study demonstrates that the fixed‐dose combination of anagliptin and metformin can be used safely in patients with type 2 diabetes complicated by moderate renal dysfunction.
Hiroshi Kajio, Ryotaro Bouchi, Mitsuhisa Komatsu, Masanori Yamazaki, Daisuke Takarabe, Masahide Okamoto, Takahisa Tanaka, Toru Kitazawa, Hisayuki Katsuyama, Yasumichi Mori, Mitsuhiko Noda   +10 more
wiley   +1 more source

The lipid-lowering effect of ezetimibe in pure vegetarians

Journal of Lipid Research, 2006
Results of previous studies have shown that ezetimibe (10 mg/day) reduces LDL cholesterol in patients with mild hypercholesterolemia on a normal-cholesterol diet (dietary intake of 200–500 mg/day) by 16–22%.
Jacob J. Clarenbach, Michael Reber, Dieter Lütjohann, Klaus von Bergmann, Thomas Sudhop   +4 more
doaj   +1 more source

Comment on “Epicardial Fat Thickness as a Marker of Coronary Artery Disease in Diabetics: A Single Center Study”

Clinical Cardiology, Volume 49, Issue 4, April 2026.
Mashal Naveed, Maheen Saeed, Muhammad Shahid Saddique, Mawra Naveed, Ahmad Furqan Anjum   +4 more
wiley   +1 more source

Myasthenia gravis following the initiation of statin therapy: A multinational self‐controlled case series study

Journal of Internal Medicine, Volume 299, Issue 4, Page 502-514, April 2026.
Abstract Background Evidence regarding the risk of new‐onset myasthenia gravis (MG) following statin therapy initiation is limited. Objectives To investigate this potential adverse effect using multinational real‐world population‐based data. Methods A self‐controlled case series (SCCS) study was conducted using electronic medical records and claims ...
Vincent Ka Chun Yan, Wanchun Xu, Yuta Taniguchi, Kwun Kei Fung, Koon Ho Chan, Gary Kui Kai Lau, Celine Sze Ling Chui, Francisco Tsz Tsun Lai, Xue Li, Masao Iwagami, Rie Masuda, Nanako Tamiya, Sreemanee Raaj Dorajoo, Jing Wei Neo, Esther Wai Yin Chan, Ian Chi Kei Wong, Eric Yuk Fai Wan   +16 more
wiley   +1 more source

Combination of Ezetimibe and Garlic Reduces Serum Lipids and Intestinal Niemann-Pick C1-like 1 Expression More Effectively in Hypercholesterolemic Mice

Avicenna Journal of Medical Biochemistry, 2015
Background Combination therapy plays an important role in the management of cardiovascular disease (CVD). Objectives The aim of this experiment was to study the influence of garlic combined with ezetimibe ...
Mohammadi, Vafaei, Nabi Moradi, Ahmadi, Pourjafar, Abbasi Oshaghi   +5 more
doaj   +1 more source

Ezetimibe alone or in combination with simvastatin increases small dense low-density lipoproteins in healthy men: a randomized trial [PDF]

, 2017
Aims The predominance of small dense low-density lipoproteins (sdLDLs) has been associated with increased cardiovascular risk. The effect of ezetimibe on LDL subfraction distribution has not been fully elucidated.
Berneis, Kaspar, Berthold, Heiner K., Gouni-Berthold, Ioanna, Krone, Wilhelm, Rizzo, Manfredi, Spinas, Giatgen A.   +5 more
core  

Electrochemical Decarboxylative Hydroxylation for the Sustainable Synthesis of Bempedoic Acid

ChemElectroChem, Volume 13, Issue 6, 17 March 2026.
A sustainable synthesis of bempedoic acid is achieved using electrochemical hydroxylative decarboxylation as the key step. Starting from Meldrum's acid, mild metal‐free alkylation, hydrolysis, and decarboxylation provide the key precursor, which is electrochemically converted to the alcohol intermediate and then hydrolyzed to the final product ...
Pietro Ronco, Antonia Simi, Enrico Lunghi, Federico Della Negra, Beatrice Trucchi, Massimo Verzini, Giuseppe Zanoni   +6 more
wiley   +1 more source

Quality and efficiency of statin prescribing across countries with a special focus on South Africa : findings and future implications [PDF]

, 2014
Statins are recommended first-line treatment for hyperlipidemia, with published studies suggesting limited differences between them. However, there are reports of under-dosing. South Africa has introduced measures to enhance generic utilization. Part one
Bishop, Iain, Campbell, Stephen M, Godman, Brian, Malmström, Rickard E, Truter, Ilse   +4 more
core   +1 more source

Efficacy and Safety of Ezetimibe Added to Atorvastatin Versus Atorvastatin Uptitration or Switching to Rosuvastatin in Patients With Primary Hypercholesterolemia [PDF]

, 2013
Hypercholesterolemic patients (n = 1,547) at high atherosclerotic cardiovascular disease risk with low-density lipoprotein cholesterol (LDL-C) levels 65100 and 64160 mg/dl while treated with atorvastatin 10 mg/day entered a multicenter, randomized ...
Averna, M., Bays, H., Brudi, P., De Pellegrin, A., Farnier, M., Giezek, H., Lee, R., Lowe, R., Majul, C., Muller Wieland, D., Triscari, J.   +10 more
core   +1 more source

Efficacy and tolerability of evolocumab vs. ezetimibe in patients with muscle-related statin intolerance: the GAUSS-3 randomized clinical trial

, 2016
Importance: Muscle-related statin intolerance is reported by 5% to 20% of patients. Objective: To identify patients with muscle symptoms confirmed by statin rechallenge and compare lipid-lowering efficacy for 2 nonstatin therapies, ezetimibe and ...
, Ballantyne, Christie M, Brennan, Danielle M, Bruckert, Eric, Ceška, Richard, Dent-Acosta, Ricardo E, Elliott, Mary, Gouni-Berthold, Ioanna, Jensen, Henrik Kjærulf, Jeppesen, Jørgen, Lehman, Sam J, Lepor, Norman, Nissen, Steven E, Preiss, David, Rosenson, Robert S, Sattar, Naveed, Scott, Rob, Somaratne, Ransi, Stein, Evan A, Stroes, Erik, Wasserman, Scott M   +20 more
core   +2 more sources