Results 111 to 120 of about 27,341 (230)

Ezetimibe and simvastatin for the prevention of cardiovascular events in predialysis chronic kidney disease patients: a review

open access: yes, 2012
Sahar Naderi,1 JoAnne M Foody21Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, OH, USA; 2Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USAAbstract: The majority of chronic kidney disease ...
Foody JM, Naderi S
core  

Ezetimibe and vascular endothelial function. [PDF]

open access: yes, 2011
Hypercholesterolemia is a major risk factor for cardiovascular diseases that has been managed mostly with 3-hydroxy-3-methyl glutaryl coenzyme A reductase inhibitors (statins) that suppress de novo cholesterol synthesis in the liver.
Maemura, Koji, Ikeda, Satoshi
core   +2 more sources

FABRICATION AND CHARACTERIZATION OF EZETIMIBE SOLID DISPERSION FOR SOLUBILITY ENHANCEMENT [PDF]

open access: yes, 2017
Objective: The objective of the present study was to formulate solid dispersions (SD) of Ezetimibe to improve the solubility and dissolution rate to facilitate faster onset of action.
E, Achadu A, Jajere, Usman Mohammed
core   +1 more source

Tirzepatide for Excess Weight in Adults With Type 1 Diabetes Using MiniMed 780G

open access: yes
Diabetes, Obesity and Metabolism, EarlyView.
Michelantonio De Fano   +6 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, Volume 13, Issue 35, 24 June 2026.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

Ezetimibe therapy: mechanism of action and clinical update

open access: yes, 2012
Binh An P Phan,1 Thomas D Dayspring,2 Peter P Toth31Division of Cardiology, Loyola University Medical Center, Maywood, IL, USA; 2Foundation for Health Improvement and Technology, Wayne, NJ, USA; 3CGH Medical Center, Sterling, IL, USAAbstract: The ...
Toth PP, Dayspring TD, Phan BAP
core  

Effect of Simvastatin-Ezetimibe Compared With Simvastatin Monotherapy After Acute Coronary Syndrome Among Patients 75 Years or Older: A Secondary Analysis of a Randomized Clinical Trial.

open access: yesJAMA cardiology, 2019
Importance Limited evidence is available regarding the benefit and hazard of higher-intensity treatment to lower lipid levels among patients 75 years or older.
R. Bach   +8 more
semanticscholar   +1 more source

Variability in ACT Response to Standard UFH Bolus During PCI: A Prospective Study on Determinants of Subtherapeutic Anticoagulation

open access: yesCatheterization and Cardiovascular Interventions, Volume 107, Issue 7, Page 2293-2303, June 1, 2026.
ABSTRACT Background Unfractionated heparin (UFH) remains the standard anticoagulant during percutaneous coronary intervention (PCI), with guidelines recommending a target activated clotting time (ACT) of ≥250 s. However, despite receiving a standardized bolus dose, many patients fail to achieve this target.
Manh Cuong Vu   +9 more
wiley   +1 more source

Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia

open access: yes, 2002
ObjectivesThe purpose of this study was to assess the efficacy and safety of ezetimibe administered with simvastatin in patients with primary hypercholesterolemia.BackgroundDespite the availability of statins, many patients do not achieve lipid targets ...
Suresh, Ramachandran   +8 more
core   +1 more source

Two Case Reports of Percutaneous Intravascular Lithotripsy for the Treatment of Severe Coronary Artery Calcification

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Severe coronary calcification is a common challenge in percutaneous coronary intervention, often resulting in suboptimal stent expansion. Intravascular lithotripsy (IVL) employs acoustic pressure waves to fracture calcified plaques and increase procedural success.
Liang‐cai Guo   +3 more
wiley   +1 more source

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