Results 231 to 240 of about 672,429 (301)

Deconvolution Analysis of G and F-Actin Unfolding: Insights into the Thermal Stability and Structural Modifications Induced by PACAP. [PDF]

Int J Mol Sci
Bukovics P, Lőrinczy D.
europepmc   +1 more source

Actuation of Cell Layers in Three Dimensions

Advanced Materials, EarlyView.
ABSTRACT The alignment of fibers and cells in living tissues affect their mechanical properties and functionality. In this context, one can draw an analogy between tissues and nematic liquid crystal elastomers. We explore this analogy by growing fibroblasts on 2D‐patterned substrates and observing the contraction of cell sheets upon detachment from the
Kirsten Endresen, Aniruddh Murali, Birte C. Geerds, Grecia M. Valenzuela Portillo, Maria Bloksgaard, Daniel J.G. Pearce, Francesca Serra   +6 more
wiley   +1 more source

Coactosin-like F-actin binding protein (Cotl1) plays a key role in adipocyte differentiation and obesity. [PDF]

Commun Biol
Park E, Jeon H, Oh KI, Jeong J, Kim DW, Jin HS, Jeong SY.   +6 more
europepmc   +1 more source

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

Advanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung, Emie Humann, Joshua M. Price, Yoav Binenbaum, Azra Haseki, Sanjana Iyer, David J. Mooney   +6 more
wiley   +1 more source

Accumulation of F-actin drives brain aging and limits healthspan in Drosophila. [PDF]

Nat Commun
Schmid ET, Schinaman JM, Liu-Abramowicz N, Williams KS, Walker DW.   +4 more
europepmc   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer's disease. [PDF]

Alzheimers Res Ther
P A H, Basavaraju N, Chandran M, Jaleel A, Bennett DA, Kommaddi RP.   +5 more
europepmc   +1 more source

ATR-hippo drives force signaling to nuclear F-actin and links mechanotransduction to neurological disorders. [PDF]

Sci Adv
Chatzifrangkeskou M, Stanly T, Koennig D, Campos-Soares L, Eyres M, Hasson A, Perdiou A, Vendrell I, Fischer R, Das S, Gardner S, Go S, Futcher B, Newton A, Skourides P, Szele F, O'Neill E.   +16 more
europepmc   +1 more source

Mechanomemory after short episodes of intermittent stresses induces YAP translocation via increasing F-actin. [PDF]

APL Bioeng
Rashid F, Njoki E, Kabbo SA, Wang N.
europepmc   +1 more source

ANKK1 Is a Wnt/PCP Scaffold Protein for Neural F-ACTIN Assembly. [PDF]

Int J Mol Sci
Domínguez-Berzosa L, Cantarero L, Rodríguez-Sanz M, Tort G, Garrido E, Troya-Balseca J, Sáez M, Castro-Martínez XH, Fernandez-Lizarbe S, Urquizu E, Calvo E, López JA, Palomo T, Palau F, Hoenicka J.   +14 more
europepmc   +1 more source