Interaction of an individual F-BAR domain with a lipid membrane.
, 2013 (A) Lipid membrane interaction with the wild type F-BAR (WT) domain (as described in simulation WT1) and F-BAR domain with positive charges on residues along the inner leaflet abolished (as described in Methods for simulation NC).
Hang Yu (278278) +1 more
core +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Curvature Sensing Mediated by F-BAR Domain and an Intrinsically Disordered Region of FBP17 [PDF]
Biophysical Journal, 2021 Maohan Su +3 more
openaire +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Phosphorylation of the F-BAR protein Hof1 drives septin ring splitting in budding yeast
Nature CommunicationsA double septin ring accompanies cytokinesis in yeasts and mammalian cells. In budding yeast, reorganisation of the septin collar at the bud neck into a dynamic double ring is essential for actomyosin ring constriction and cytokinesis.
Maritzaida Varela Salgado +8 more
doaj +1 more source
Multiplicity of solutions for biharmonic equations with critical exponent and prescribed singularity
Electronic Journal of Differential EquationsIn this article, we study the singular critical biharmonic problem $$\displaylines \Delta^2u-\mu V(x)u=|u|^{2^*-2}u+\lambda f(x) \quad \text{in } \Omega, \\ u= \frac{\partial u}{\partial n}=0 \quad \text{on } \partial \Omega, }$$ where \( \Delta^2 ...
Nadjet Yagoub +3 more
doaj +1 more source
Opposite Surfaces of the Cdc15 F-BAR Domain Create a Membrane Platform That Coordinates Cytoskeletal and Signaling Components for Cytokinesis. [PDF]
Cell Rep, 2020 Snider CE +7 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source