Results 71 to 80 of about 1,113,401 (243)
Self-assembly of CIP4 drives actin-mediated asymmetric pit-closing in clathrin-mediated endocytosis
Nature Communications, 2023 Clathrin-mediated endocytosis is pivotal to signal transduction pathways between the extracellular environment and the intracellular space. Evidence from live-cell imaging and super-resolution microscopy of mammalian cells suggests an asymmetric ...
Yiming Yu, Shige H. Yoshimura
doaj +1 more source
Energies, 2022 When an induction motor is running at stable speed and low slip, the fault signal of the induction motor’s broken bar faults are easily submerged by the power frequency (50 Hz) signal. Thus, it is difficult to extract fault characteristics. The left-side
Xinyue Liu +6 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Domains of Injectivity for the Gross-Hopkins Period Map [PDF]
, 2015 We determine the domain of injectivity of the Gross-Hopkins Period map around each points in the deformation space for a fixed formal module $\bar{F}$ of height 2 that defined over a finite field.
Lo, Chi Yu
core
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
A solution to the Pompeiu problem [PDF]
, 2013 Let $f \in L_{loc}^1 (\R^n)\cap \mathcal{S}$, where $\mathcal{S}$ is the Schwartz class of distributions, and $$\int_{\sigma (D)} f(x) dx = 0 \quad \forall \sigma \in G, \qquad (*)$$ where $D\subset \R^n$ is a bounded domain, the closure $\bar{D}$ of ...
Ramm, A. G.
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A quasilinear problem with fast growing gradient
, 2012 In this paper we consider the following Dirichlet problem for the $p$-Laplacian in the positive parameters $\lambda$ and $\beta$: [{{array} [c]{rcll}% -\Delta_{p}u & = & \lambda h(x,u)+\beta f(x,u,\nabla u) & \text{in}\Omega u & = & 0 & \text{on}\partial\
Bueno, Hamilton, Ercole, Grey
core +1 more source