Results 141 to 150 of about 15,333,834 (330)

Computing the elliptic genus of higher rank E-strings from genus 0 GW invariants

Journal of High Energy Physics, 2019
We show that the elliptic genus of the higher rank E-strings can be computed based solely on the genus 0 Gromov-Witten invariants of the corresponding elliptic geometry.
Zhihao Duan, Jie Gu, Amir-Kian Kashani-Poor   +2 more
doaj   +1 more source

D-brane and F-theory Model Building [PDF]

, 2022
Fernando Marchesano, Bert Schellekens, Timo Weigand   +2 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

On the scarcity of weak coupling in the string landscape

Journal of High Energy Physics, 2018
We study the geometric requirements on a threefold base for the corresponding F-theory compactification to admit a weakly-coupled type IIB limit. We examine both the standard Sen limit and a more restrictive limit, and determine conditions sufficient for
James Halverson, Cody Long, Benjamin Sung   +2 more
doaj   +1 more source

The origin of discrete symmetries in F-theory models [PDF]

, 2015
George K Leontaris
openalex   +1 more source

Anisotropic spacetimes in $f(T,B)$ theory III: LRS Bianchi III Universe [PDF]

, 2022
Genly León, Andronikos Paliathanasis
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Hamiltonian Brownian motion in Gaussian thermally fluctuating potential. I. Exact Langevin equations, invalidity of Marcovian approximation, common bottleneck of dynamic noise theories, and diffusivity/mobility 1/f noise [PDF]

, 2013
Yu. E. Kuzovlev
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A viable form of the metric Teleparallel F(T) theory of gravity [PDF]

, 2023
Manas Chakrabortty, Nayem Sk, Abhik Kumar Sanyal   +2 more
openalex   +2 more sources