Results 131 to 140 of about 11,553,390 (309)
Computing the elliptic genus of higher rank E-strings from genus 0 GW invariants
Journal of High Energy Physics, 2019 We show that the elliptic genus of the higher rank E-strings can be computed based solely on the genus 0 Gromov-Witten invariants of the corresponding elliptic geometry.
Zhihao Duan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
On the scarcity of weak coupling in the string landscape
Journal of High Energy Physics, 2018 We study the geometric requirements on a threefold base for the corresponding F-theory compactification to admit a weakly-coupled type IIB limit. We examine both the standard Sen limit and a more restrictive limit, and determine conditions sufficient for
James Halverson +2 more
doaj +1 more source
Five-Brane Superpotentials and Heterotic/F-theory Duality
, 2010 Under heterotic/F-theory duality it was argued that a wide class of heterotic five-branes is mapped into the geometry of an F-theory compactification manifold.
Ha, Tae-Won +5 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
R-Parity violation in F-Theory
, 2016 We discuss R-parity violation (RPV) in semi-local and local F-theory constructions. We first present a detailed analysis of all possible combinations of RPV operators arising from semi-local F-theory spectral cover constructions, assuming an $SU(5)$ GUT.
Stephen F. King +9 more
core +1 more source
Anomalies of (0,4) SCFTs from F-theory [PDF]
, 2020 We study the macroscopics of 2d N = (0, 4) SCFTs arising from F-theory constructions. The class of 2d SCFTs we consider live on black strings which are obtained by wrapping D3-branes on a curve in the base of a possibly singular elliptically fibered ...
Couzens, Christopher +3 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source