Results 141 to 150 of about 15,537,269 (305)
Zoology of complex threefold bases in F-theory
, 2018 I'm going to present algorithms that explicitly generate a large number of topologically distinct smooth toric threefold bases used in 4D F-theory compactification. We found inherent patterns in these bases although they are seemingly random.
Wang, Yinan
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
R-Parity violation in F-Theory
, 2016 We discuss R-parity violation (RPV) in semi-local and local F-theory constructions. We first present a detailed analysis of all possible combinations of RPV operators arising from semi-local F-theory spectral cover constructions, assuming an $SU(5)$ GUT.
Stephen F. King +9 more
core +1 more source
Anomalies of (0,4) SCFTs from F-theory [PDF]
, 2020 We study the macroscopics of 2d N = (0, 4) SCFTs arising from F-theory constructions. The class of 2d SCFTs we consider live on black strings which are obtained by wrapping D3-branes on a curve in the base of a possibly singular elliptically fibered ...
Couzens, Christopher +3 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Neutrino mass textures from F-theory
, 2013 Experimental data on the neutrino mixing and masses strongly suggest an underlying approximate symmetry of the relevant Yukawa superpotential terms. Intensive phenomenological explorations during the last decade indicate that permutation symmetries such ...
Antoniadis, I. +3 more
core +1 more source
Mordell—Weil lattice and the global gauge group of F-theory
, 2018 The global gauge group structure of F-theory compactifications is tied to the embedding of the Mordell—Weil lattice into the Neron—Severi group, also known as the Shioda map. While this has been previously explored in the case of purely non-abelian gauge
Lin, Ling
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Viable and stable compact stars in $$f({\mathcal {Q}})$$ f ( Q ) theory
European Physical Journal C: Particles and FieldsIn this paper, we study the viability and stability of anisotropic compact stars in the context of $$f({\mathcal {Q}})$$ f ( Q ) theory, where $${\mathcal {Q}}$$ Q is non-metricity scalar.
Muhammad Zeeshan Gul +3 more
doaj +1 more source