Results 151 to 160 of about 11,553,390 (309)

Zoology of complex threefold bases in F-theory

open access: yes, 2018
I'm going to present algorithms that explicitly generate a large number of topologically distinct smooth toric threefold bases used in 4D F-theory compactification. We found inherent patterns in these bases although they are seemingly random.
Wang, Yinan
core  

Higher-Derivative Corrected Black Holes: Perturbative Stability and Absorption Cross-Section in Heterotic String Theory

open access: yes, 2006
This work addresses spherically symmetric, static black holes in higher-derivative stringy gravity. We focus on the curvature-squared correction to the Einstein-Hilbert action, present in both heterotic and bosonic string theory.
Schiappa, R.   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Prepotential, Mirror Map and F-Theory on K3

open access: yes, 1998
We compute certain one-loop corrections to F^4 couplings of the heterotic string compactified on T^2, and show that they can be characterized by holomorphic prepotentials.
Stieberger, S., Lerche, W.
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Physics and Geometry of F-theory 2017

open access: yes, 2017
The goal of this conference is to bring together the experts in the field of F-theory from around the globe, both from the physics and the mathematics community, in order to exchange ideas about recent progress and future endeavours.

core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Mordell—Weil lattice and the global gauge group of F-theory

open access: yes, 2018
The global gauge group structure of F-theory compactifications is tied to the embedding of the Mordell—Weil lattice into the Neron—Severi group, also known as the Shioda map. While this has been previously explored in the case of purely non-abelian gauge
Lin, Ling
core  

F-theory vacua with $\mathbb Z_3$ gauge symmetry

open access: yes, 2015
Discrete gauge groups naturally arise in F-theory compactifications on genus-one fibered Calabi-Yau manifolds. Such geometries appear in families that are parameterized by the Tate-Shafarevich group of the genus-one fibration.
Piragua, Hernan   +9 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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