When the electrochemical proton gradient is disrupted in the mitochondria, IF1 (Inhibitor Factor-1) inhibits the reverse hydrolytic activity of the F1Fo-ATP synthase, thereby allowing cells to conserve ATP at the expense of losing the mitochondrial ...
L P Fernández-Cárdenas +5 more
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While mechanisms controlling uncoupling protein-1 (UCP1) in thermogenic adipocytes play a pivotal role in non-shivering thermogenesis, it remains unclear whether F1Fo-ATP synthase function is also regulated in brown adipose tissue (BAT).
Henver S Brunetta +15 more
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F1FO ATP synthase mutants in Chlamydomonas: Stability and oligomycin resistance mediated by atypical Asa7 protein; interaction between chloroplastic and mitochondrial bioenergetics [PDF]
Marie Lapaille +9 more
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Mechanisms of Selective Sodium/Proton Binding and Coupled Rotation in F1fo ATP Synthases: Insights from Quantitative Computer Simulations [PDF]
Alexander Krah +2 more
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Beneficial effect of polyphenols in COVID-19 and the ectopic F1 FO -ATP synthase: Is there a link? [PDF]
Panfoli I, Esposito A.
europepmc +1 more source
Heterologous expression, purification and crystallization on central stalk and peripheral stalk of F1FO ATP synthase of Aquifex aeolicus [PDF]
Shuai Xin +4 more
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What Makes You Can Also Break You, Part II: Mitochondrial Permeability Transition Pore Formation by Dimers of the F1FO ATP-Synthase? [PDF]
György Szabadkai, Christos Chinopoulos
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Mitochondrial cristae ultrastructure enables ATP synthase organization for adaptive energy production. This process is critical for regulating microglia mediated neuroinflammation in ischemic stroke pathology.
Xiao-Wen Zhang +17 more
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Cytoplasmic Loops of Subunits C and A in E. Coli F1Fo ATP Synthase Interact to Gate H+ Transport to the Cytoplasm [PDF]
Robert Fillingame
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Structural studies of the membrane-embedded c-ring of the F1FO-ATP synthase from a thermoalkaliphilic bacterium reveal a strategy for adaptation to alkaline environments [PDF]
Doreen Matthies +8 more
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