Results 171 to 180 of about 15,996 (213)
F35. Prevalence of nerve conduction abnormalities in type 1 diabetes mellitus
Introduction Diabetic peripheral neuropathy (DPN) is the commonest microvascular complication in diabetic patients. Unlike type-2 DM, children with type-1 DM rarely develop the classical features of neuropathy. Nerve conduction study (NCS) is an objective, non-invasive electrophysiological test for diagnosing DPN The aim of this study is to detect and
Hana Ahmed
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Intracellular trafficking and fate of chimeric adenovirus 5/F35 in human B lymphocytes
AbstractBackgroundInvestigation of the molecular processes that control the development and function of lymphocytes is essential for our understanding of humoral immunity, as well as lymphocyte‐associated pathogenesis. Adenovirus‐mediated gene transfer provides a powerful tool for investigating these processes.
Mélanie Samson, Daniel Jung
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2023
The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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2018
Trenched evaluation at RAF Lakenheath identified an area of Late Neolithic/Early Bronze Age occupation underlying deposits of windblown sand that were seen all across the evaluation area. The remnants of an undated cremation burial and an undated ditch were also found.
Smart, R., Brroks, R.
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Trenched evaluation at RAF Lakenheath identified an area of Late Neolithic/Early Bronze Age occupation underlying deposits of windblown sand that were seen all across the evaluation area. The remnants of an undated cremation burial and an undated ditch were also found.
Smart, R., Brroks, R.
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Genetic modification of effector lymphocytes, such as T cells and natural killer (NK) cells, is essential for many approaches to gene-based immunotherapy of cancer. However, transduction of lymphocytes has proven difficult by currently available gene transfer methods.
Roland Schroers +6 more
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Phase 2A Study of Ad5.F35-hGCC-PADRE in Gastrointestinal Malignancies
Kernel Networks Inc.
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Adenoviral gene transfer into human B lymphocytes and haematopoietic progenitors would allow the characterization of their function on cellular growth, differentiation and survival. Efficient gene expression is however strongly dependent on the promoter used.
Marie‐Pierre Cayer +9 more
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AbstractBackgroundConditionally replicative adenovirus (CRAd) provides a promising strategy for solid tumor therapy. However, relatively few studies have been addressed on hematopoietic malignancies. We previously found that ZD55, a serotype 5 (Ad5)‐based, E1B 55‐kDa deleted CRAd, inhibited leukemic cell growth and induced apoptosis.
Guohua Wang +8 more
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Clinical Cancer Research, 2006
AbstractPurpose: Expression of the FHIT protein is lost or reduced in most solid tumors and a significant fraction of hematopoietic malignancies. Adenovirus 5 (Ad5) virus or adeno-associated viral vectors have been used to study the tumor suppressor function of FHIT in solid tumors, but these tools have not been effective in leukemias.
PICHIORRI F +9 more
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AbstractPurpose: Expression of the FHIT protein is lost or reduced in most solid tumors and a significant fraction of hematopoietic malignancies. Adenovirus 5 (Ad5) virus or adeno-associated viral vectors have been used to study the tumor suppressor function of FHIT in solid tumors, but these tools have not been effective in leukemias.
PICHIORRI F +9 more
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Efficient gene transfer into normal human B lymphocytes with the chimeric adenoviral vector AD5/F35
Journal of Immunological Methods, 2005The failure to efficiently introduce genes into normal cells such as human B lymphocytes limits the characterization of their function on cellular growth, differentiation and survival. Recent studies have shown that a new adenoviral vector Ad5/F35 can efficiently transduce human haematopoietic CD34+ progenitor cells. In this study, we compared the gene
Daniel, Jung +3 more
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