Results 181 to 190 of about 13,969 (210)

Molecular Dynamics Analysis of FAAH Complexed with Anandamide

2015
Fatty Acid Amide Hydrolase (FAAH) is a very interesting serine hydrolase that promotes the hydrolysis of both amides and esters, such as the endogenous cannabinoid anandamide or N-arachidonoyl ethanolamine (AEA), and the sleep-inducing lipid oleamide.
Sérgio F. Sousa, João T. S. Coimbra, MARINO, Tiziana, Pedro A. Fernandes, Maria J. Ramos, RUSSO, Nino   +5 more
openaire   +2 more sources

The FAAH inhibitor URB597 efficiently reduces tyrosine hydroxylase expression through CB₁- and FAAH-independent mechanisms.

British journal of pharmacology, 2014
Anandamide and 2-arachidonoylglycerol are neuromodulatory lipids interacting with cannabinoid receptors, whose availability is regulated by the balance between 'on demand' generation and enzymatic degradation [by fatty acid amide hydrolase (FAAH)/monoacylglycerol lipase].
Barbara, Bosier, Giulio G, Muccioli, Didier M, Lambert   +2 more
openaire   +1 more source

FAAH

2010
Joris C Verster, Thomas M. Tzschentke, Kieran O’Malley, Francis C Colpaert, Bart Ellenbroek, Bart Ellenbroek, R. Hamish McAllister-Williams, Joachim Liepert, Cecilia J. Hillard, Sheldon Preskorn, Megan M Dahmen, Janka Lincoln, Oliver Stiedl, Sven Ove Ögren, E C Warburton, Bernard Le Foll, Mohammed Shoaib, Victoria L Harvey, Tony Dickenson, Ennio Esposito, Roberto William Invernizzi, Ennio Esposito, Robert William Invernizzi, Edoardo Spina, Cyril Höschl, Kim Wolff, Andreas Marneros, Anthony L. Riley, Steve Kohut, Samuel R. Chamberlain, Barbara J. Sahakian, David C.S. Roberts, Joseph Zohar, Seiya Miyamoto, Malcolm Lader, Emma Childs, Lawrence H. Price, Harriet de Wit, Wolfgang Fleischhacker, Lance Richard McMahon, Bernard Le Foll, Bernard Le Foll, Lawrence H. Price, Kieran O’Malley, Kieran O’Malley, Stephen M. Stahl, Meghan M Grady, Stephen C Fowler, Francis C. Colpaert, Alex Hofer, Etienne Sibille, Nicole Edgar, Linda P. Spear, Sam Hutton, Linda Lundstroem, Silvia Gatti McArthur, Will Spooren, Maria Isabel Colado, Richard Green, Marcy J. Bubar, Kathryn A Cunningham, Stephan G. Anagnostaras, Jennifer R Sage, Stephanie A. Carmack, Peter H. Boeijinga, Peter H. Boeijinga, Paul Newhouse, Heather Wilkins, Gary Remington, John Atack, Hilde Lavreysen   +70 more
openaire   +1 more source

A perspective review on fatty acid amide hydrolase (FAAH) inhibitors as potential therapeutic agents

European Journal of Medicinal Chemistry, 2020
Rati Kailash Prasad Tripathi
exaly  

FAAH

2013
openaire   +1 more source

Bial incident raises FAAH suspicions

Nature Biotechnology, 2016
openaire   +1 more source

A FAAH-fetched approach to treat osteoarthritis pain

Pain, 2011
Aron H, Lichtman, Victoria, Chapman
openaire   +2 more sources

Potential application of endocannabinoid system agents in neuropsychiatric and neurodegenerative diseases—focusing on FAAH/MAGL inhibitors

Acta Pharmacologica Sinica, 2020
Zhen-Zhen Wang, Yi Zhang
exaly  

FAAH-1

2013
openaire   +1 more source

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor

ACS Medicinal Chemistry Letters, 2011
Benjamin F Cravatt
exaly