Results 31 to 40 of about 28,757,677 (326)
Complement Factor H-Related Protein 4A Is the Dominant Circulating Splice Variant of CFHR4
Recent research has elucidated circulating levels of almost all factor H-related (FHR) proteins. Some of these proteins are hypothesized to act as antagonists of the important complement regulator factor H (FH), fine-tuning complement regulation on human
Richard B. Pouw +8 more
doaj +1 more source
Anti-factor H antibody and its role in atypical hemolytic uremic syndrome
Atypical hemolytic uremic syndrome (aHUS) an important form of a thrombotic microangiopathy (TMA) that can frequently lead to acute kidney injury (AKI). An important subset of aHUS is the anti-factor H associated aHUS.
Rupesh Raina +8 more
doaj +1 more source
C3 Glomerulonephritis associated with Anti-complement Factor H Autoantibodies in an Adolescent Male: A Case Report [PDF]
C3 glomerulonephritis (C3GN), a rare condition associated with dysregulation of the alternative pathway of the complement system, is histopathologically characterized by isolated or dominant C3 deposition in the renal glomeruli.
HyeSun Hyun +4 more
doaj +1 more source
The effect of human factor H on immunogenicity of meningococcal native outer membrane vesicle vaccines with over-expressed factor H binding protein. [PDF]
The binding of human complement inhibitors to vaccine antigens in vivo could diminish their immunogenicity. A meningococcal ligand for the complement down-regulator, factor H (fH), is fH-binding protein (fHbp), which is specific for human fH.
Peter T Beernink +5 more
doaj +1 more source
The following asymptotic result is proved. For every \(\varepsilon> 0\), and for every positive integer \(h\), there exists an \(n_0= n_0(\varepsilon, h)\) such that for every graph \(H\) with \(h\) vertices and for every \(n> n_0\), any graph \(G\) with \(hn\) vertices and with minimum degree \[ d\geq \Biggl({\chi(H)- 1\over \chi(H)}+ \varepsilon ...
Raphael Yuster, Noga Alon
openaire +2 more sources
Recombinant human factor H (hFH) has potential for treating diseases linked to aberrant complement regulation including C3 glomerulopathy (C3G) and dry age-related macular degeneration.
Heather Kerr +18 more
doaj +1 more source
Complement factor H in host defense and immune evasion
Complement is the major humoral component of the innate immune system. It recognizes pathogen- and damage-associated molecular patterns, and initiates the immune response in coordination with innate and adaptive immunity.
Raffaella Parente +3 more
semanticscholar +1 more source
An $H$-factor of a graph $G$ is a spanning subgraph of $G$ whose connected components are isomorphic to $H$. Given a properly edge-colored graph $G$, a rainbow $H$-subgraph of $G$ is an $H$-subgraph of $G$ whose edges have distinct colors. A rainbow $H$-factor is an $H$-factor whose components are rainbow $H$-subgraphs.
openaire +2 more sources
H. pylori virulence factors [PDF]
Among people infected with Helicobacter pylori, the virulence of the infecting strain is a major determinant of who develops disease. Strains producing vacuolating cytotoxin activity are more commonly isolated from people with peptic ulcers than without.
openaire +3 more sources
On factor width and symmetric H-matrices [PDF]
The factor width of a real symmetric matrix \(A\) is the smallest integer \(k\) such that there exists a real rectangular matrix \(V\) such that \(A=VV^T\) and each column of \(V\) contains at most \(k\) nonzero entries. It is proven that the set of symmetric real matrices with factor width at most two coincides with the class of generalized diagonally
Doron Chen +3 more
openaire +2 more sources

