Results 111 to 120 of about 14,184,553 (374)
Molecular Oncology, Volume 19, Issue 4, Page 1054-1074, April 2025.The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits +7 more
wiley +1 more source
Coagulation Factor IX for Hemophilia B Therapy
Acta Naturae, 2012 Factor IX is a zymogen enzyme of the blood coagulation cascade. Inherited absence or deficit of the IX functional factor causes bleeding disorder hemophilia B, which requires constant protein replacement therapy.
N. Orlova +3 more
semanticscholar +1 more source
OCD factorization for the pion diffractive dissociation into two jets [PDF]
arXiv, 2001 We present main ideas and obtained results of our recent calculations of Coulomb and QCD contribution to the pion diffractive dissociation into two jets.
arxiv
Towards a mouse model for haemophilia [PDF]
, 1992 Haemophilias A and B are X-linked recessive bleeding disorders caused by deficiencies of coagulation factors VIII and IX respectively. Present treatment for the disease, by replacement therapy with products extracted from large volumes of pooled blood ...
Kenny, Raechel
core
Performance of AAV8 vectors expressing human factor IX from a hepatic-selective promoter following intravenous injection into rats [PDF]
, 2008 Background: Vectors based on adeno-associated virus-8 (AAV8) have shown efficiency and efficacy for liver-directed gene therapy protocols following intravascular injection, particularly in relation to haemophilia gene therapy. AAV8 has also been proposed
Baker, AH +4 more
core +2 more sources
Molecular Oncology, Volume 19, Issue 4, Page 1188-1202, April 2025.Male infertility is a known risk factor for the development of testicular cancer. In this paper, we analyzed the expression profile of a microRNA panel by real‐time PCR and validated the results by digital PCR. Experimental and bioinformatics analyses allowed us to identify possible biomarkers able to discern men with a higher risk of developing ...
Carmen Ferrara +14 more
wiley +1 more source
Algebraic model of an oblate top [PDF]
Symmetries in Science IX, 9 (1997), 1996 We consider an algebraic treatment of a three-body system. In particular, we develop the formalism for a system of three identical objects and discuss an application to nonstrange baryon resonances which are interpreted as vibrational and rotational excitations of an oblate symmetric top.
arxiv
Enhancement of pulmonary tumour seeding by human coagulation factors II, IX, X--an investigation into the possible mechanisms involved. [PDF]
, 1991 Warfarin inhibits metastasis in the animal model and injection of the Warfarin-dependent coagulation factor complex II, IX, X enhances pulmonary metastasis in the same model.
George, W. D. +2 more
core +2 more sources
Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis
Molecular Oncology, Volume 19, Issue 4, Page 1002-1028, April 2025.Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch +11 more
wiley +1 more source
Direct reactions in/for astrophysics [PDF]
PoSNIC-IX:040,2006, 2006 Precise nuclear reaction rates are needed for a detailed description of the production of elements in primordial nucleosynthesis and during the hydrostatic burning of stars to constrain the astrophysical models. The relevant reactions are extremely difficult to measure directly in the laboratory at the small astrophysical energies.
arxiv