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Radiologic technology, 2020 Factor V Leiden thrombophilia is a genetic mutation that results in hypercoagulation of the blood that presents life-threatening symptoms. This article describes the role of imaging in diagnosis and treatment of cardiovascular complications caused by factor V Leiden and summarizes the etiology, risk factors, symptoms, diagnostic measures, progression ...
Jason S, Applegate, Diane, Gronefeld
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Managing the Complexity of Thrombotic and Bleeding Risks: Case Report of Factor VII Deficiency and Factor V Leiden Mutation in a Patient With Bi-valvular Infective Endocarditis Undergoing Open-heart Surgery. [PDF]
J Community Hosp Intern Med PerspectShyam T +10 more
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Circulation, 2003 You may have been tested for the condition known as factor V Leiden (pronounced factor five lye/-den) because you or someone in your family has had a blood clot in one of the deep veins of the body (also called deep vein thrombosis, or DVT) or a blood clot that traveled to the lung (also called a pulmonary embolism, or PE).
Deborah L. Ornstein, Mary Cushman
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Factor V Leiden and Inflammation [PDF]
Thrombosis, 2012 Factor V Leiden, is a variant of human factor V (FV), also known as proaccelerin, which leads to a hypercoagulable state. Along these years, factor V Leiden (FVL) has been studied from the pathophysiologic point of view, and research has been focused on finding clinical approaches for the management of the FVL associated to a trombophilic state.
Silvia Perez-Pujol +2 more
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Complications of Mesenteric Vein Thrombosis: Heterozygous Factor V Leiden Mutation Leads to Pulmonary Embolism in a Patient With Post-Bowel Resection Surgery. [PDF]
Clin Case RepHamza HM +5 more
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Factor V Leiden thrombophilia [PDF]
Genetics in Medicine, 2011 Factor V Leiden is a genetic disorder characterized by a poor anticoagulant response to activated Protein C and an increased risk for venous thromboembolism. Deep venous thrombosis and pulmonary embolism are the most common manifestations, but thrombosis in unusual locations also occurs.
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Factor V Leiden, prothrombin, MTHFR, and PAI-1 gene polymorphisms in patients with arterial disease: A comprehensive systematic-review and meta-analysis [PDF]
, 2023 Emanuele Valeriani +5 more
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Mechanisms of the Factor V Leiden Paradox [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2008 Objective— Carriers of the factor V Leiden mutation (FVL-carriers) have a substantially increased risk of deep venous thrombosis (DVT), whereas the risk of pulmonary embolism (PE) is only mildly increased compared with noncarriers.
van Stralen, K. J. +5 more
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Factor V Leiden Mutation and Pregnancy [PDF]
The Journal of the American Board of Family Medicine, 2004 Factor V Leiden mutation (FVL) is an autosomal dominant hemostatic disorder that predisposes affected persons to venous thromboembolic events (VTE). Although the mutation causing FVL is easily diagnosed using molecular DNA techniques,[1][1] patients who are heterozygous for this disorder ...
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Factor V Leiden and Cardiopulmonary Bypass
The Journal of ExtraCorporeal Technology, 2015 We present a case of a patient with factor V Leiden with an antithrombin III activity of 67% who received a successful aortic valve replacement supported by cardiopulmonary bypass (CPB). A safe level of anticoagulation was achieved by monitoring activated clotting time (ACT) and heparin concentration ensuring adequate anticoagulation throughout the ...
Victor, Uppal +5 more
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