Results 141 to 150 of about 644,115 (313)

Ancylostoma caninum Anticoagulant Peptide: A novel inhibitor of coagulation factor Xa with potent antimetastatic activity. • 650 [PDF]

, 1997
Kathleen M. Donnelly, Michael Bromberg, William H. Konigsberg, Michael Cappello   +3 more
openalex   +1 more source

A comprehensive review of cluster methods for drug–drug interaction network

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract The detection of drug–drug interaction (DDI) is crucial to the rational use of drug combinations. Experimentally, DDI detection is time‐consuming and laborious. Currently, researchers have developed a variety of computational methods to predict DDI.
Shuyuan Cao, Guixia Liu, Xiangrun Zhou, Ji Lv   +3 more
wiley   +1 more source

Use of Andexanet Alfa for Factor Xa Inhibitor Reversal in US Verified Trauma Centers: A National Survey

Clinical and Applied Thrombosis/Hemostasis
Direct oral factor Xa inhibitors are replacing vitamin K-dependent antagonists as anticoagulation treatment in many clinical scenarios. Trauma centers are noting an increase in patients presenting on these medications.
Charles Fasanya MD, FRCS FACS, Abenámar Arrillaga MD FACS FCCP, Catherine Caronia MD, MBA, Lauren Rothburd BS, Tenzing Japhe BA, Younghee Hahn BS, Paul Joseph BS, Dajana Reci BA, Patricia Eckardt PhD, RN, FAAN   +8 more
doaj   +1 more source

Clinical Outcomes of First Metatarsophalangeal Joint Arthrodesis Using the BOFAS Registry: A Prospective Cohort Study

Journal of Foot and Ankle Research, Volume 18, Issue 4, December 2025.
ABSTRACT Background This study investigated the quality and clinical outcomes of the British Orthopaedic Foot and Ankle Society (BOFAS) registry first metatarsophalangeal joint (MTPJ) arthrodesis pathway. Methods A prospective cohort study using data derived from the BOFAS registry.
Ferozkhan Jadhakhan, Makwana Nilesh, Mason Lyndon, Halliwell Paul, Rushton Alison   +4 more
wiley   +1 more source

Modes of binding synthetic inhibitors to factor Xa: an automated docking approach [PDF]

, 1996
Mohan Rao, Arthur J. Olson
openalex   +1 more source

Impact of Direct Oral Anticoagulant Uptake on Hospitalizations for Stroke/Transient Ischemic Attack, Intracranial Hemorrhage, and Gastrointestinal Bleeding in Individuals With Atrial Fibrillation: A Population‐Based Study

Fundamental &Clinical Pharmacology, Volume 39, Issue 6, December 2025.
ABSTRACT Background Direct‐acting oral anticoagulants (DOACs) have largely replaced warfarin for stroke prevention in patients with atrial fibrillation, yet their population‐level impact on health outcomes and costs remains unclear. We examined whether the widespread uptake of DOACs was associated with changes in hospitalization rates and costs for ...
Tony Antoniou, Daniel McCormack, Tianru Wang, Mina Tadrous, Tara Gomes   +4 more
wiley   +1 more source

Laboratory practice on detection of antiphospholipid antibodies: UK NEQAS blood coagulation survey—2024

British Journal of Haematology, EarlyView.
Deepa J. Arachchillage, Mike Laffan, Will Lester, Steve Kitchen, Ian Jennings   +4 more
wiley   +1 more source

Lower risk of cardiovascular events in patients initiated on semaglutide 2.4 mg in the real‐world: Results from the SCORE study (Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity in the Real World)

Diabetes, Obesity and Metabolism, Volume 27, Issue 11, Page 6691-6704, November 2025.
Abstract Aims In this first interim analysis of the SCORE study, we investigated the risk of major adverse cardiovascular events (MACE) among individuals with atherosclerotic cardiovascular disease (ASCVD) and overweight/obesity but without diabetes who initiated semaglutide 2.4 mg in real‐world settings.
Kim G. Smolderen, Carlos Mena‐Hurtado, Zhenxiang Zhao, Wojciech Michalak, Mads Faurby, B. Gabriel Smolarz, Mikhail N. Kosiborod, Jinlin Song, Yan Chen, Joanna Boland, Michael G. Nanna   +10 more
wiley   +1 more source

Serine 380 (P14) → Glutamate Mutation Activates Antithrombin as an Inhibitor of Factor Xa [PDF]

, 2000
Akiko Futamura, Peter G.W. Gettins
openalex   +1 more source

Prorenin in Hepatic Stellate Cell Extracellular Vesicles Induces Platelet‐Dependent Thrombin Formation and Release of Profibrotic TGF‐β

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Platelets interact with extracellular vesicles shed by hepatic stellate cells to activate both cell types. Extracellular vesicles shed by activated hepatic stellate cells contain inactive prorenin. HSC‐EV interact with quiescent platelets to non‐proteolytically activate ligated prorenin.
Rui Chen, Emily Huang, Xianfang Wu, Megan R. McMullen, Xianjia Wang, Laura E. Nagy, Ge Jin, Scott J. Cameron, Thomas M. McIntyre   +8 more
wiley   +1 more source