Results 71 to 80 of about 644,115 (313)

Factor Xa Inhibitors Versus Vitamin K Antagonists for Prevention of Cerebral or Systemic Embolism in Patients With Atrial Fibrillation

Cochrane Database of Systematic Reviews, 2018
BACKGROUND Factor Xa inhibitors and vitamin K antagonists (VKAs) are now recommended in treatment guidelines for preventing stroke and systemic embolic events in people with atrial fibrillation (AF).
K. B. Bruins Slot, E. Berge
semanticscholar   +1 more source

MnI‐Functionalized Covalent Organic Framework as Efficient Electrocatalyst for CO2 Reduction in a Catholyte‐Free Zero‐Gap Electrolyzer

Advanced Functional Materials, EarlyView.
This work demonstrates the successful integration of a phenanthroline‐based 2D COF with MnI catalytic sites into a catholyte‐free membrane‐electrode‐assembly cell for CO2 electroreduction. The crystalline COF actively suppresses Mn⁰–Mn⁰ dimerization, achieving a turnover frequency of 617 h⁻¹ at 2.8 V (full‐cell potential), and enabling stable operation.
Laura Spies, Marcos Eduardo G. Carmo, Gonçalves J. Marrenjo, Stephan Reuther, Patrick Ganswindt, Antonio Otavio T. Patrocinio, Thomas Bein, Osmando F. Lopes, Jenny Schneider   +8 more
wiley   +1 more source

Direct oral anticoagulant blood level monitoring in daily practice

Thrombosis Update, 2021
Introduction: Routine monitoring is not required in direct oral anticoagulant (DOAC) treatment, yet it is frequently performed. Guidance on the interpretation and management of DOAC level measurements is lacking and it is key to investigate which ...
R. Bavalia, J.E. Veenhuizen, R.C.C. Hengeveld, D. Braeken, A.J.W. Gulpen, H. Ten Cate, S. Middeldorp, Y.M.C. Henskens, B.A. Hutten, M. Coppens, A.K. Stroobants   +10 more
doaj   +1 more source

Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages [PDF]

, 2009
Malaria pathology is caused by multiplication of asexual parasites within erythrocytes, whereas mosquito transmission of malaria is mediated by sexual precursor cells (gametocytes).
Beitz, Billker, Bork, Bystrom, CCP4, Daily, Darbon, Deitsch, Duraisingh, Emsley, Feese, Fivelman, Gouet, Greenwood, Guan, Hansen, Herzberg, Holz, Hurley, Hurley, Liu, Mair, McCabe, Murshudov, Ormo, Perrakis, Promeneur, Roudier, Sambrook, Santiago, Sharp, Studier, Trager, Vagin, Vial, Witteveen, Yeh, Young   +37 more
core   +4 more sources

Advanced Air Electrodes for Reversible Protonic Ceramic Electrochemical Cells: A Comprehensive Review

Advanced Materials, EarlyView.
Reversible protonic ceramic electrochemical cells (R‐PCECs) face challenges from sluggish and unstable oxygen reduction and evolution reactions in the air electrode. This review discusses recent progress in triple‐conducting air electrodes, emphasizing mechanisms, performance factors, and design strategies, offering guidance for creating efficient and ...
Xi Chen, Yeshu Tan, Zheng Li, Tong Liu, Yinghao Song, Shuo Zhai, Na Yu, Zongping Shao, Meng Ni   +8 more
wiley   +1 more source

Mechanistic Basis for the Differential Effects of Rivaroxaban and Apixaban on Global Tests of Coagulation

TH Open, 2018
Rivaroxaban and apixaban are both small molecules that reversibly inhibit factor Xa. Compared with rivaroxaban, apixaban has minimal effects on the prothrombin time and activated partial thromboplastin time.
Paul Y. Kim, Calvin H. Yeh, Brian J. Dale, Beverly A. Leslie, Alan R. Stafford, James C. Fredenburgh, Jack Hirsh, Jeffrey I. Weitz   +7 more
doaj   +1 more source

Antiagregación y anticoagulación en síndromes coronarios agudos: niveles de evidencia [PDF]

, 2007
Management of acute coronary syndromes (ACS) has moved rapidly in parallel with our understanding of the pathophysiological basis of the disease. In the eighties, the demonstration of the pivotal role of coronary thrombosis in the etiology of a ACS led ...
Garcia, R. (R.), Paramo, J.A. (José Antonio), Rodriguez, P. (P.), Ruiz-de-Gaona, E. (Estefanía)   +3 more
core  

NOACs versus warfarin for stroke prevention in patients with AF : a systematic review and meta-analysis [PDF]

, 2016
Acknowledgments Revman software was used for meta-analysis, a free download from the Cochrane Collaboration. GRADE pro software was used to formulate the GRADE summary of findings table, a free download from the GRADE working group.Peer reviewedPublisher
Eisinga, Anne, Hicks, Tim, Stewart, Fiona   +2 more
core   +1 more source

Anti-Xa Activity and Event Risk in Patients With Direct Factor Xa Inhibitors Initiated Early After Stroke.

Circulation Journal, 2018
BACKGROUND Measuring anti-Xa activity (AXA) has been reported as useful for predicting future risk of hemorrhagic and ischemic events in stroke patients taking direct factor Xa inhibitors.
S. Wada, K. Toyoda, Shoichiro Sato, T. Matsuki, T. Okata, M. Kumamoto, Naoki Tagawa, M. Inoue, A. Okamoto, M. Ihara, T. Kitazono, T. Miyata, M. Koga   +12 more
semanticscholar   +1 more source

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang, Taihe Zhou, Yueming Sun, Yuanchen Ma, Yiwen Deng, Keyu Chen, Ruijie Li, Yuan Qiu, Tao Wang, Xiaoyong Chen, Li Huang, Lu Zhu, Xueyi Tu, Ying Wang, Zheming Liu, Rouchen Lin, Yunli Tong, Yuantao Li, Heshe Li, Lin Nie, Rui Fang, Jianqi Feng, Xuhong Wei, Xia Feng, Andy Peng Xiang, Xiaoran Zhang   +25 more
wiley   +1 more source