Results 221 to 230 of about 2,109,479 (260)

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

Advanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang, Dongzhi Wang, Yafei Guo, Qi Zheng, Min Zhang, James Simmonds, Jian Hou, Xuemei Liu, Xuelei Lin, Xiaomin Bie, Xiansheng Zhang, Xiaohui Li, Yuan Chen, Xueyong Zhang, Cristobal Uauy, Fei Lu, Chengcai Chu, Zhixi Tian, Jun Xiao   +18 more
wiley   +1 more source

Liver‐Targeted Gallium‐Polyphenol Network by Disrupting the ROS/NETs/PANoptosis Axis for Precision Acute Liver Injury Therapy

Advanced Science, EarlyView.
ABSTRACT Acute liver injury (ALI), driven by diverse insults such as drug toxicity and ischemia‐reperfusion, poses a high mortality risk and lacks targeted therapies. While reactive oxygen species (ROS), neutrophil extracellular traps (NETs), and a coordinated cell death pathway PANoptosis have been implicated, their interplay as a unified pathogenic ...
Xiaopeng Cai, Jian He, Jingwen Deng, Ziwei Wang, Zhongshu Wu, Kaiyue Wang, Xiang Zheng, Zhenzhen Gao, Xi Ma, Shumei Wei, Xiangrong Hu, Yuan Ding, Weilin Wang, Min Zhou   +13 more
wiley   +1 more source

Factor XI Deficiency in apoE/FXI Double-Knockout Mice Decreases Atherosclerosis by Lowering <i>MSR1</i> mRNA Expression Within the Plaque. [PDF]

J Lipid Atheroscler
Shnerb Ganor R, Paraboschi EM, Stefano D, Harats D, Asselta R, Schiby G, Leichner GS, Anekstein Spigel M, Tamarin I, Kandel Kfir M, Steinberg DM, Shaish A, Salomon O.   +12 more
europepmc   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

A Rare Case of Hereditary Factor XI Deficiency Accompanied by Lupus Anticoagulant in an Adult Patient with Monoclonal Gammopathy of Undetermined Significance. [PDF]

Intern Med
Liu H.
europepmc   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

Advanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua, Anira Escrichs, Yonatan Sanz Perl, Morten L. Kringelbach, Adele Diamond, Solange Denervaud, Gustavo Deco   +6 more
wiley   +1 more source

Integrating Machine Learning With Constant‐Potential Simulation to Unravel Charge‐Transfer Mechanisms in Electrochemical Nitrogen Fixation

Advanced Science, EarlyView.
Integrating interpretable machine learning with the fixed‐potential method reveals a novel mechanism: the catalytic activity of the electrochemical nitrogen reduction reaction is governed by partial charge transfer, induced by variations in the intermediate potential of zero charge under constant potential.
Yufei Xue, Dushuo Feng, Yuefei Zhang, Yang Zhang, Yalong Jiao, Aijun Du, Guoping Gao   +6 more
wiley   +1 more source

Recombinant Activated Factor VIIa Combined With Tranexamic Acid Control Haemostasis in Patients With Severe Factor XI Deficiency Undergoing Urological Procedures. [PDF]

Haemophilia
Sternbach N, Ehrlich Y, Stenevsky A, Saidian D, Elhalim DA, Baniel J, Raanani P, Spectre G.   +7 more
europepmc   +1 more source

A Systematic Review of Safety and Efficacy of Factor XI/XIa Inhibitors in Patients With ESKD on Hemodialysis. [PDF]

Kidney Int Rep
Steiner D, Kraemmer D, Nopp S, Königsbrügge O, Ay C.   +4 more
europepmc   +1 more source

Novel horizons in anticoagulation: the emerging role of factor XI inhibitors across different settings. [PDF]

Haematologica
Cohen O, Santagata D, Ageno W.
europepmc   +1 more source