Results 171 to 180 of about 15,171,266 (336)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

FACTORES DE RIESGO EXTRALABORAL Y NIVELES DE ESTRÉS PRESENTES EN LOS ESTUDIANTES DE POSGRADO DE LA ESPECIALIZACIÓN EN SEGURIDAD Y SALUD EN EL TRABAJO, EN LA MODALIDAD VIRTUAL DE TRES INSTITUCIONES DE EDUCACIÓN SUPERIOR

Revista Ingeniería, Matemáticas y Ciencias de la Información
Los niveles de estrés han presentado un incremento significativo gracias a los diferentes estresores a los cuales se enfrenta la población a nivel general.
Gina Yurley Fuentes Rojas
doaj   +1 more source

K-Factores en nubes bicromáticas [PDF]

, 2007
Consideramos una colección de puntos bicromática y nos preguntamos cuántos puntos adicionales son necesarios considerar para asegurar la existencia de un k {factor.
Atienza Martínez, María Nieves, Cortés Parejo, María del Carmen, Garijo Royo, Delia, Grima Ruiz, Clara Isabel, Valenzuela Muñoz, Jesús, Villar Liñán, María Trinidad   +5 more
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Factores que afectan el comportamiento reproductivo de los cerdos en el noreste de México. I. Tamaño de la camada y promedio de peso de los lechones.

Revista Mexicana de Ciencias Pecuarias, 1992
Se utilizó la Información de 988 camadas al nacer y 640 camadas al destete de una piara comercial en el Noreste de México. EI clima de la región es semiárido con temperatura media de 23 C y precipitación pluvial al año de 634 mm.
Ricardo Ramírez Gómez, José C Segura Correa   +1 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

[Response to comment on the article "Incidence and factors associated with delirium in an Emergency Department"]. [PDF]

Rev Med Inst Mex Seguro Soc
Ayón-Aguilar J, Serrano-Vértiz L, Quiroz-Lara FV, Torres-Macotela M.   +3 more
europepmc   +2 more sources

Factores que afectan el comportamiento reproductivo de los cerdos en el noreste de México. II. Periodo de gestación e intervalo entre partos.

Revista Mexicana de Ciencias Pecuarias, 1992
Se utilizó la información de 923 periodos de gestación (PG) y 458 intervalos entre partos (IEP) tomada de los registros reproductivos de 198 marranas de una piara comercial en San Fernando, Tamaulipas, México.
Ricardo Ramírez Gómez, José C Segura Correa   +1 more
doaj  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source