Results 121 to 130 of about 14,368 (309)
Least Order Coprime Factorizations of Rational Matrices: The Canonical Case
, 1998 Given an arbitrary real rational matrix G and a domain Gamma g in the closed complex plane we develop a complete theory of coprime factorizations of G over Gamma g having denominators of least possible McMillan degree.
Varga, A., Oara, C.
core
On Matrix Factorization and Scheduling for Finite-Time Average-Consensus [PDF]
, 2010 We study the problem of communication scheduling for finite-time average-consensus in arbitrary connected networks. Viewing this consensus problem as a factorization of 1/n 11T by network-admissible families of matrices, we prove the existence of finite
Ko, Chih-Kai
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Sparse block factorization of saddle point matrices [PDF]
, 2014 The factorization method presented in this paper takes advantage of the special structures and properties of saddle point matrices. A variant of Gaussian elimination equivalent to the Cholesky's factorization is suggested and implemented for factorizing ...
Schilders, W.H.A. +2 more
core +1 more source
Factorization-based versus alignment-based methods.
, 2020 (A) Factorization-based single-view learning methods. They typically factorize a data matrix X from single view (e.g., gene expression matrix of samples by genes) into a product of matrix G (coefficient matrix) and matrix (dictionary matrix or pattern ...
Nam D. Nguyen (8661216) +1 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Factorization of Holomorphic Matrices and Kazhdan's Property (T)
In this article we deduce some algebraic properties for the group Sp_{2n}(O(X)) of holomorphic symplectic matrices on a Stein space X: holomorphic factorization, exponential factorization, and Kazhdan's property (T).
Schott, Josua +2 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source