Results 151 to 160 of about 4,357,899 (292)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Faculty development and career success in clinical teaching. [PDF]

Int J Med Educ
Huang AY, Yeh WY, Lin EJ, Liang JF, Yang YY, Hsu PT, Huang CC, Huang SS, Yang SJH, Chen CH.   +9 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Letter Re: "Faculty Development and Support in Orthopedic Education: A Narrative Review". [PDF]

J Orthop Case Rep
Ahmad M, Bohler F.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Acceptability and feasibility of a faculty development programme for medical and dental academics in Ghana. [PDF]

BMC Med Educ
Konadu AB, Nyarko ENY, Opoku KA, Tormeti D, Hottor AB, Drovandi A, Yawson EA, Hewlett S, Banyubala DN, Hart J, Conen S, Siriwardhana DD, Harris S, Grundy J, Byrne-Davis L.   +14 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

MORALE AND FACULTY DEVELOPMENT IN AGRICULTURAL ECONOMICS [PDF]

Morale and faculty development are closely related. The agricultural economics profession must decide what it is about. There is room to practice the principle of comparative advantage and allow a degree of specialization in teaching, extension, and ...
Purcell, Wayne D.
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

From resistance to readiness: faculty development as the key to AI literacy in public health. [PDF]

Front Public Health
Acosta JA.
europepmc   +1 more source