Results 91 to 100 of about 8,833,991 (337)
Second law of thermodynamics and the failure of rock materials [PDF]
, 2001 The relation of nonequilibrium thermodynamics to some failure and fracture theories of rock mechanics is investigated. The basic concepts are given to connect failure to the properties of material equations describing the elastic properties.
Ván, Péter, Vásárhelyi, Balázs
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
BMC Cardiovascular Disorders, 2019 Background The function of deiodinases – selenoproteins converting thyroid hormones may be disturbed by oxidative stress accompanying heart failure. Selenium (Se) may be used by glutathione peroxidase, leading to a lack of deiodinase and triiodothyronine
Magdalena Fraczek-Jucha +6 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Understanding and Mitigating Extrapolation Failures in Physics-Informed Neural Networks [PDF]
, 2023 Lukas Fesser +2 more
openalex +1 more source
Guoji laonian yixue zazhi[Objective] To investigate the correlation of mitochondrial DNA copy number (mtDNAcn), Klotho protein, myostatin (MSTN) and their combination with physical frailty in elderly patients with sarcopenia.
Zhou Yanyan +5 more
doaj +1 more source
The efficiency of “quasimarkets”—decentralized public goods provision subjected to Tiebout competition—is a staple of public choice conventional wisdom.
Boettke, Peter +2 more
core +1 more source
Fatigue failure load indicator [PDF]
, 1979 An indicator for recording the load at which a fatigue specimen breaks during the last cycle of a fatigue test is described. A load cell is attached to the specimen which is alternately subjected to tension and compression loads.
Davis, D. C., Davis, W. T., Imig, L. A.
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source