Results 101 to 110 of about 266,152 (301)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
A Simple Three-dimensional Failure Criterion for Rocks Based on the Hoek–Brown Criterion
, 2015 A simple three-dimensional (3D) failure criterion for rocks is proposed in this study. This new failure criterion inherits all the features of the Hoek–Brown (HB) criterion in characterizing the rock strength in triaxial compression, and also accounts ...
Zhao, Jidong, Jiang, Hua
core +1 more source
Failure assessment of a woven E-glass/vinyl ester composite subjected to large deformation loading
Science and Engineering of Composite Materials, 2012 Woven polymer-based composites exhibit highly non-linear behavior, which often results in very high strains to failure. A micromechanical model is developed to represent the large deformation kinematics of woven composites, and develop predictions for ...
Hufner David R. +2 more
doaj +1 more source
Implementation of a constitutive model for anisotropic rocks based on modified Lade failure criterion. [PDF]
Sci Rep, 2023 Liu X, Deng Y, Zou B.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Nonlinear failure criterion in the Mohr plane .
, 2019 Nonlinear failure criterion in the Mohr plane .
Xin Zhang (35492) +4 more
core +1 more source
An Innovative Failure Criterion for Metal Cylindrical Shells under Explosive Loads. [PDF]
Materials (Basel), 2022 Li Y, Wang W, Chen Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Numerical and Experimental Studies for Fatigue Damage Accumulation of CFRP Cross-Ply Laminates Based on Entropy Failure Criterion. [PDF]
Materials (Basel), 2022 Deng H +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source