Results 121 to 130 of about 4,757,745 (346)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Modeling Progressive Damage and Failure of Single-Lap Thin-Ply-Laminated Composite-Bolted Joint Using LaRC Failure Criterion. [PDF]

Materials (Basel), 2022
Wang X, Wang Y, Ji Y, Hu H, Cao D, Zheng K, Liu H, Li S.   +7 more
europepmc   +1 more source

Combining mechanical and chemical effects in the deformation and failure of a cylindrical electrode particle in a Li-ion battery

, 2014
A general framework to study the mechanical behaviour of a cylindrical silicon anode particle in a lithium ion battery as it undergoes lithiation is presented.
Chakraborty, Jeevanjyoti, Chapman, S. Jonathan, Goriely, Alain, Please, Colin P.   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Multiscale and Failure Analysis of Periodic Lattice Structures

Applied Sciences
A full-cycle, multiscale analysis technique was developed for periodic lattice structures with geometric repetition, aiming for more efficient modeling to predict their failure loads.
Young Kwon, Matthew Minck
doaj   +1 more source

A Plane Stress Failure Criterion for Inorganically-Bound Core Materials. [PDF]

Materials (Basel), 2021
Lechner P, Hartmann C, Ettemeyer F, Volk W.   +3 more
europepmc   +1 more source

Geometric Auslander criterion for openness of an algebraic morphism

, 2013
We give an effective criterion for openness of a morphism of schemes of finite type over a field: Over a normal base of dimension n, failure of openness is detected by a vertical component in the n'th fibred power of the morphism.
Adamus, Janusz, Bierstone, Edward, Milman, Pierre D.   +2 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

True triaxial test and failure criterion of coal gangue concrete

Meitan xuebao
In view of the pollution caused by the large storage of coal gangue and the shortage of natural aggregate in concrete, using coal gangue as coarse aggregate is a reasonable way to solve the above problems.
Weiping ZHAO, Yuxiang HE, Kongliang JIANG, Jiaqi YANG, Yang XU, Jialong CHEN   +5 more
doaj   +1 more source

A Reliable Fracture Angle Determination Algorithm for Extended Puck's 3D Inter-Fiber Failure Criterion for Unidirectional Composites. [PDF]

Materials (Basel), 2021
Gong Y, Huang T, Zhang X, Jia P, Suo Y, Zhao S.   +5 more
europepmc   +1 more source