Results 81 to 90 of about 233,228 (266)

An Innovative Failure Criterion for Metal Cylindrical Shells under Explosive Loads. [PDF]

Materials (Basel), 2022
Li Y, Wang W, Chen Z.
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Numerical and Experimental Studies for Fatigue Damage Accumulation of CFRP Cross-Ply Laminates Based on Entropy Failure Criterion. [PDF]

Materials (Basel), 2022
Deng H, Mochizuki A, Fikry M, Abe S, Ogihara S, Koyanagi J.   +5 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Performance Assessment of Self-Healing Polymer-Modified Bitumens by Evaluating the Suitability of Current Failure Definition, Failure Criterion, and Fatigue-Restoration Criteria. [PDF]

Materials (Basel), 2023
Lv S, Ge D, Wang Z, Wang J, Liu J, Ju Z, Peng X, Fan X, Cao S, Liu D, Zhang W, Borges Cabrera M.   +11 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Critical Analysis of “Maximum Stress Failure Criterion” for Composite Materials

The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2009
The paper deals with critical considerations upon different points of view that were enounced by some authors referring to Maximum Stress Failure Criterion for composite materials. The considerations stem both from a comparative analysis of the mentioned
Ion FUIOREA, Dumitriţa STĂNICĂ
doaj  

Numerical-computational analysis of reinforced concrete structures considering the damage, fracture and failure criterion

Revista IBRACON de Estruturas e Materiais
The experimental results of testing structures or structural parts are limited and, sometimes, difficult to interpret. Thus, the development of mathematical-numerical models is needed to complement the experimental analysis and allow the generalization ...
L. A. F. de Souza, R. D. Machado
doaj   +1 more source

Modeling Progressive Damage and Failure of Single-Lap Thin-Ply-Laminated Composite-Bolted Joint Using LaRC Failure Criterion. [PDF]

Materials (Basel), 2022
Wang X, Wang Y, Ji Y, Hu H, Cao D, Zheng K, Liu H, Li S.   +7 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source