Results 51 to 60 of about 7,431,248 (353)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Reliability Analysis Model [PDF]
, 1970 RAM program determines probability of success for one or more given objectives in any complex system. Program includes failure mode and effects, criticality and reliability analyses, and some aspects of operations, safety, flight technology, systems ...
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Audit Laporan Failure Mode and Effect Analysis (Fmea) Produk Ga Rear Motor Wiper Berdasarkan Objektif Kualitas Pada PT. Xyz [PDF]
, 2015 PT XYZ using FMEA report GA Rear Wiper which is adopted from PT XYZ Jepang and they has not made the adjustment to the condition in the production floor. This cause will create the failure process that can be evaluated from the percentage of defect.
Kumala, A. (Amelia), Rumita, R. (Rani)
core
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Finite Element Analysis of FRP Debonding Failure at the Tip of Flexural/Shear Crack in Concrete Beam [PDF]
, 2013 One of the most common failure modes of strengthened RC beams with externally bonded FRP is intermediate crack (IC) debonding of FRP initiated at the tip of flexural/shear cracks. This study presents a method, using extended finite element method (XFEM),
Harries, Kent +2 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Energy Exploration & Exploitation, 2022 The macroscopic failure of concrete used to form an artificial dam in an underground coal mine reservoir is the final manifestation of crack propagation and penetration: the mode of crack propagation is key to the safety evaluation of concrete structures.
Xianjie Hao +5 more
doaj +1 more source
Fatigue of friction stir welded 2024-T351 aluminium alloy
, 2002 Fatigue failure characteristics of friction stir welds in 13mm gauge 2024-T351 plate have been assessed. Failure occurred from either the weld region (nugget/flow arm) or from the material immediately surrounding the weld.
Booth, D., Sinclair, I.
core +1 more source