Results 71 to 80 of about 52,035 (209)

UPAYA ELITE KERAJAAN ISLAM DALAM MOBILISASI DUKUNGAN PADA PEMILIHAN KEPALA DAERAH KABUPATEN FAK-FAK PROVINSI PAPUA BARAT TAHUN 2016 [PDF]

, 2019
Pemilihan kepala daerah adalah suatu proses demokrasi dimana mengharuskan di setiap daerah harus melakukan regenerasi kepemimpinan di suatu daerah. Dalam pemilihan kepala deerah di Kabupaten Fak-Fak tahun 2016 ada hal menarik dimana Raja-Raja Kerajaan ...
Mafa Uswanas, 071411333024
core   +1 more source

Focal adhesion kinase regulates the activity of the osmosensitive transcription factor TonEBP/NFAT5 under hypertonic conditions

Frontiers in Physiology, 2014
TonEBP/NFAT5 is a major regulator of the urinary concentrating process and is essential for the osmoadaptation of renal medullary cells. Focal adhesion kinase (FAK) is a mechanosensitive non-receptor protein tyrosine kinase expressed abundantly in the ...
Wolfgang eNeuhofer
doaj   +1 more source

CB1 Cannabinoid Receptors Stimulate Gβγ-GRK2-Mediated FAK Phosphorylation at Tyrosine 925 to Regulate ERK Activation Involving Neuronal Focal Adhesions

Frontiers in Cellular Neuroscience, 2020
CB1 cannabinoid receptors (CB1) are abundantly expressed in the nervous system where they regulate focal adhesion kinase (FAK) and the mitogen-activated protein kinases (MAPK) extracellular signal-regulated kinase 1 and 2 (ERK1/2).
George D. Dalton, Skyla T. Carney, Jamie D. Marshburn, Derek C. Norford, Allyn C. Howlett   +4 more
doaj   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception

Advanced Science, EarlyView.
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li   +7 more
wiley   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

FAK-heterozygous mice display enhanced tumour angiogenesis [PDF]

, 2013
Genetic ablation of endothelial focal adhesion kinase (FAK) can inhibit pathological angiogenesis, suggesting that loss of endothelial FAK is sufficient to reduce neovascularization.
Jones, DT, Robinson, Stephen D, Baker, M, Delphine M. Lees, Kairbaan Hodivala-dilke, Parsons, Madeline; id_orcid, Reynolds, Louise E., Dylan T. Jones, Robinson, Stephen R., Parsons, Maddy, Hart, IR, Anna M. R, Ramjuan, Antoine R., Baker, Marianne, Tanguy Lechertier, Parsons, M, Tavora, B, Bernardo Tavora, Lechertier, Tanguy, Hart, Ian R., Kostourou, V, Stephen D. Robinson, Lechertier, T, Reynolds, Louise E, Birdsey, GM, Lees, Delphine M, Vassiliki Kostourou, Ramjaun, AR, Louise E. Reynolds, Marianne Baker, Hodivala-Dilke, K, Randi, AM, Randi, Anna M, Reynolds, LE, Jones, Dylan T., Hodivala-Dilke, Kairbaan, Tavora, Bernardo, Birdsey, Graeme M., Birdsey, Graeme M, Ramjaun, Antoine R, Randi, Anna M., Jones, Dylan T, Antoine R. Ramjaun, Robinson, SD, Lees, DM, Graeme M, Maddy Parsons, Ian R Harta, Lees, Delphine M., Kostourou, Vassiliki, Hart, Ian R   +50 more
core   +1 more source

Mechanically Regulated Secretion: How Physical Forces Instruct the Secretory Pathway and Remodel the Secretome

Advanced Science, EarlyView.
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo, Seetharaman Parashuraman, Maria Luigia Maresca, Angela Francesca Dinoi, Alessia Calcagnì, Riccardo Rizzo   +5 more
wiley   +1 more source

Erasmus Çerçevesinde Akademik Ürdün Seyahatimiz

İlahiyat Tetkikleri Dergisi, 2016
ERASMUS + HOCA DEĞİŞİMİÜNİVERSİTELER: ATATÜRK ÜNİVERSİTESİÜRDÜN DEVLET ÜNİVERSİTESİBİRİMLER : İlahiyat Fakültesi- Kulliyyetu’ş-Şerî’aSüre : 19-24 Mart 2016ÜLKE-ŞEHİR : ÜRDÜN-AmmanKatılımcılar :Prof. Dr. Davut YAYLALI: İlahiyat Fak. DekanıProf. Dr.
Sadık KILIÇ
doaj   +1 more source

Expression of phosphorylated Pyk2 in FAK+/+ and FAK−/− osteoblasts.

, 2013
Expression and localization of phosphorylated Pyk2 at Tyr-402 (red) in FAK+/+ (A) and FAK−/− (B) osteoblasts. DAPI nuclei stain in blue. Magnification = 60×. Scale bar represents 25 µm.
Kristen L. Lee (306199), Nikitha Reddy Yereddi (306200), Shefali Kumar (306202), W. Joyce Tang (306203), Jennifer T. Blundo (306197), Jae-Beom Kim (25395), Alesha B. Castillo (306196), Eugene Jang (306201), Sarah Zarrin (306204), Julia C. Chen (306198), Christopher R. Jacobs (306205)   +10 more
core   +1 more source