Results 41 to 50 of about 2,113,119 (309)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Automatic fall detectors and the fear of falling [PDF]

Journal of Telemedicine and Telecare, 2004
We studied the effect of automatic fall detection units on the fear of falling. Participants were community alarm users living in the community aged over 75 years or those aged 60–74 years who had experienced a fall in the previous six months. Of those approached, 31% consented to take part; the main reason given for potential participants declining ...
Brownsell, Simon, Hawley, Mark
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A principal components approach to parent-to-newborn body composition associations in South India [PDF]

, 2009
Background: size at birth is influenced by environmental factors, like maternal nutrition and parity, and by genes. Birth weight is a composite measure, encompassing bone, fat and lean mass. These may have different determinants. The main purpose of this
Fall, CHD, Veena, Sargoor R, Veena Sargoor R, Krishnaveni, Ghattu V, Wills, AK, Fall Caroline HD, Wills, Andrew K., Hill, Jacqueline C, Wills, Andrew K, Veena, Sargoor R., Hill Jacqueline C, Veena, SR, Fall, Caroline Hd, Krishnaveni, Ghattu V., Hill, Jacqueline C., Krishnaveni, GV, Hill, JC, Fall, Caroline H.D., Wills Andrew K, Krishnaveni Ghattu V   +19 more
core   +1 more source

Investigation and analysis on fall risk assessment and fall status of the elderly people living in an island community (海岛社区老年人跌倒风险评估和跌倒现况调查分析)

中西医结合护理, 2022
Objective To understand the fall risk and fall status of the elderly living in an island community, to explore the influencing factors of falls, and to provide basis for the formulation of health education program.
HUANG Yanhong (黄艳红), PENG Linchun (彭林川), ZHENG Yulong (郑余龙), SHI Ping (史平)   +3 more
doaj   +1 more source

Falls and Fall Prevention [PDF]

, 2016
About a third of older persons fall at least once a year, but less than 5 % of these falls result in a fracture. Wrist fractures usually involve a fall onto the outstretched arm. Proximal humerus fractures occur following a fall on the adducted arm. Hip fractures and fractures of the pelvic ring occur after a fall on the side.
Reiner Bartl, Christoph Bartl
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Yield of Leukocytosis in Predicting Brain Computed Tomography Pathological Findings in Pediatric Patients with Head Traumatic Injuries

Saudi Journal of Emergency Medicine, 2023
BBackground: Head trauma is an urgent medical condition that is prevalent in pediatric patients. The association between white blood cell (WBC) counts and their prognostic value in pediatric traumatic brain injury has been proposed in multiple studies ...
Bsaim Abdulsalam Altirkistani, Abdulaziz M. Alghamdi, Abdullah Osama Abukhodair, Yazeed Mohammed Alzahrani, Najeeb Qublan Alqarni   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Comparison of Humpty Dumpty and Buch Scales For Assessment of Fall Risk Among Pediatric Patients

Journal of Behçet Uz Children's Hospital, 2019
INTRODUCTION: The aim of this study is to determine the predictive validity of the Humpty Dumpty and BUCH scales in the assessment of the fall risk of child patients.
Nuray Çetintaş, Aysel Gürkan
doaj   +1 more source