Results 51 to 60 of about 4,739,983 (297)

False negative results from using common PCR reagents

BMC Research Notes, 2011
Background The sensitivity of the PCR reaction makes it ideal for use when identifying potentially novel viral infections in human disease. Unfortunately, this same sensitivity also leaves this popular technique open to potential contamination with ...
Atwood Allison A, Cummings Jessica L, Sobek Kathryn M, Bacich Dean J, O'Keefe Denise S   +4 more
doaj   +1 more source

Analysis of Negative Results of Metagenomics Next-Generation Sequencing in Clinical Practice

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundMetagenomics next-generation sequencing (mNGS) has been increasingly used in the clinic, which provides a powerful tool for the etiological diagnosis of infectious diseases.
Mengjia Qian, Bijun Zhu, Yanxia Zhan, Lingyan Wang, Qi Shen, Miaomiao Zhang, Lei Yue, Duojiao Wu, Hao Chen, Xiangdong Wang, Xiangdong Wang, Yunfeng Cheng, Yunfeng Cheng, Yunfeng Cheng, Yunfeng Cheng   +14 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

False-negative cases on long-axis view images with anteroseptal infarction with regional abnormal wall motion circled in red.

, 2022
False-negative cases on long-axis view images with anteroseptal infarction with regional abnormal wall motion circled in red.
Atsushi Teramoto (6338672), Ryosuke Muraki (12152308), Akira Yamada (509460), Eiichi Watanabe (790904), Kunihiko Sugimoto (12152311), Keiko Sugimoto (129038)   +5 more
core   +1 more source

Sequencing Shorter cfDNA Fragments Decreases the False Negative Rate of Non-invasive Prenatal Testing

Frontiers in Genetics, 2020
Circulating fetal cell-free DNA (cfDNA) is generally shorter than maternal cfDNA. Size selection of shorter cfDNA in total cfDNA could significantly increase the fetal fraction, but there are few reports of using this method to decrease the false ...
Ying Xue, Ying Xue, Guodong Zhao, Guodong Zhao, Longwei Qiao, Longwei Qiao, Jiafeng Lu, Jiafeng Lu, Bin Yu, Ting Wang, Ting Wang   +10 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Anchoring effects in the development of false childhood memories [PDF]

, 2009
When people receive descriptions or doctored photos of events that never happened, they often come to remember those events. But if people receive both a description and a doctored photo, does the order in which they receive the information matter?
Nash, Robert Alastair, K. A. Wade, R. A. Nash, Garry, Maryanne, Wade, Kimberley A., Nash, RA, Harper, DN, D. N. Harper, M. Garry, Garry, M, Harper, David N., Wade, KA   +11 more
core   +1 more source

mpt64 mutations in Mycobacterium tuberculosis with negative MPT64 antigen assay results from a tertiary hospital in Southeastern China

Frontiers in Medicine
BackgroundMPT64 protein is an effective marker for detecting Mycobacterium tuberculosis (MTB) in liquid culture and clinical tissue samples. However, some MTB clinical isolates test negative for this antigen because of varied mutation types across ...
Xinling Pan, Sujuan Zhou, Lulu Jin, Songjun Ji, Xingxing Lou, Bin Lu, Jin Zhao   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

True or false? The contested terrain of false allegations [PDF]

, 2013
This paper aims to contribute to and clarify the debate around false allegations of sexual assault by providing a summary of recent literature, including consideration of the classifications and methods of defining a false allegation, whether there is
Cindy Tarczon, Liz Wall
core